Specific T cells targeting Staphylococcus aureus fibronectin‐binding protein 1 induce a type 2/type 1 inflammatory response in sensitized atopic dermatitis patients

Background Atopic dermatitis (AD) is one of the most common inflammatory skin diseases worldwide and Staphylococcus aureus colonization and secondary infections occur in the majority of AD patients. Allergic sensitizations against microbial antigens have been discussed as possible trigger factors of...

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Veröffentlicht in:	Allergy (Copenhagen) 2022-04, Vol.77 (4), p.1245-1253
Hauptverfasser:	Farag, Ahmed K., Roesner, Lennart M., Wieschowski, Susanne, Heratizadeh, Annice, Eiz‐Vesper, Britta, Kwok, William W., Valenta, Rudolf, Werfel, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens antigen‐specific T cells Atopic dermatitis Carrier Proteins - metabolism Cell lines Cytokines Cytokines - metabolism Dermatitis Dermatitis, Atopic Eczema Epitopes Fibronectin Fibronectins - metabolism fibronectin‐binding protein 1 Helper cells Histocompatibility antigen HLA Humans Hypersensitivity Immunodominance Immunoglobulin E Lymphocytes T Major histocompatibility complex Original ORIGINAL ARTICLES Peptides Skin Skin diseases Staphylococcal Infections - metabolism Staphylococcus aureus Virulence
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