The temporal relationship between phospholipase activation, diradylglycerol formation and superoxide production in the human neutrophil

Fluctuations in the amounts of choline, inositol 1,4,5-trisphosphate (IP3) and diradylglycerol have been used to monitor phospholipase activation in the human neutrophil. Stimulation of human neutrophils by formylmethionyl-leucylphenylalanine (fMet-Leu-Phe) resulted in a rapid activation of both pho...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical journal 1990-10, Vol.271 (1), p.209-213
Hauptverfasser:	Thompson, N T, Tateson, J E, Randall, R W, Spacey, G D, Bonser, R W, Garland, L G
Format:	Artikel
Sprache:	eng
Schlagworte:	Choline - blood Diglycerides - blood Enzyme Activation Humans Inositol 1,4,5-Trisphosphate - blood Kinetics N-Formylmethionine Leucyl-Phenylalanine - pharmacology Neutrophils - metabolism Phosphatidylinositol Diacylglycerol-Lyase Phospholipase D - blood Phosphoric Diester Hydrolases - blood Superoxides - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!