Effects of functional polymorphisms of opioid receptor mu 1 and catechol‐O‐methyltransferase on the neural processing of pain

Aim Pain is reconstructed by brain activities and its subjectivity comes from an interplay of multiple factors. The current study aims to understand the contribution of genetic factors to the neural processing of pain. Focusing on the single‐nucleotide polymorphism (SNP) of opioid receptor mu 1 (OPR...

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Veröffentlicht in:	Psychiatry and clinical neurosciences 2024-05, Vol.78 (5), p.300-308
Hauptverfasser:	Cheong, Yongjeon, Lee, Seonkyoung, Okazawa, Hidehiko, Kosaka, Hirotaka, Jung, Minyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	brain and pain Catechol Catechol O-methyltransferase Cerebellum Cognitive ability Cortex (cingulate) Gene polymorphism Genetic factors Information processing Methyltransferase Narcotics Neural coding Neuroimaging opioid receptor mu 1 Opioid receptors (type mu) Pain Regular Saliva Single-nucleotide polymorphism Somatosensory cortex Temporal cortex Temporal gyrus
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