miR‑1343‑3p inhibits autophagy by directly targeting ATG7 in multiple myeloma cells

Multiple myeloma (MM) is the second most common type of hematological malignancy globally. Despite application of several new drugs, such as daratumumab, bortezomib/lenalidomide/dexamethasone, in combination with hematopoietic stem cell transplantation, overall prognosis remains poor and the patholo...

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Veröffentlicht in:	Biomedical reports 2024-12, Vol.21 (6), p.185, Article 185
Hauptverfasser:	Guo, Yanrong, Ding, Xiaoxiao, Dai, Changling, Wang, Wenwen, Chen, Jianlin, Chen, Sai, Yang, Linjun, Chen, Guang
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Apoptosis Autophagy B cells Biotechnology industry Bone marrow Bortezomib Cell culture Cell cycle Cell growth Cell survival Development and progression Dexamethasone Gene expression Genes Hematology Hematopoietic stem cells Immunosuppressive agents Infection Malignancy MicroRNA MicroRNAs miRNA Multiple myeloma Ovarian cancer Prognosis Proteins Reverse transcription Stem cell transplantation Stem cells Thyroid cancer Transfection Transplantation Tumors
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