Dimerization activates the Inversin complex in C. elegans

Genetic, colocalization, and biochemical studies suggest that the ankyrin repeat-containing proteins Inversin (INVS) and ANKS6 function with the NEK8 kinase to control tissue patterning and maintain organ physiology. It is unknown whether these three proteins assemble into a static "Inversin co...

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Veröffentlicht in:	Molecular biology of the cell 2024-10, Vol.35 (10), p.ar127
Hauptverfasser:	Beyrent, Erika, Wei, Derek T, Beacham, Gwendolyn M, Park, Sangwoo, Zheng, Jian, Paszek, Matthew J, Hollopeter, Gunther
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ankyrin Repeat Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Dimerization Optogenetics - methods Phenotype Protein Multimerization Protein Serine-Threonine Kinases - genetics Protein Serine-Threonine Kinases - metabolism
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