Synthesis, Characterization, and In-Vitro Evaluation of Silibinin-loaded PEGylated Niosomal Nanoparticles: Potential Anti-Cancer Effects on SW480 Colon Cancer Cells

Colorectal cancer is a significant global health concern with high mortality rates. Silibinin is a compound derived from milk thistle with anticancer properties and may be a potential treatment option for colorectal cancer. Its poor solubility limits its clinical application, but various strategies,...

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Veröffentlicht in:	Asian Pacific Journal of Cancer Prevention 2024-07, Vol.25 (7), p.2539-2550
Hauptverfasser:	Alali, Urjwan, Mohammed Kadhim Al-Tu'ma, Maha, Fadhil Jawad, Ammar, Talib Ahmed, Saja, Addai Ali, Hanaa, Abdulzehra, Siham, Jawad Al-Tu'ma, Fadhil
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Cell Cycle - drug effects Cell Line, Tumor Cell Proliferation - drug effects Colonic Neoplasms - drug therapy Colonic Neoplasms - pathology Drug Delivery Systems - methods Humans Liposomes - chemistry Nanoparticles - chemistry Polyethylene Glycols - chemistry Silybin - chemistry Silybin - pharmacology Tumor Cells, Cultured
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