Anti-Angiogenic and Anti-Proliferative Activity of 4-2-(5-bromo-1H-indol-2-carbonyl)-N-(4-methoxyphenyl) Hydrazine-1-carbothioamide: Ex-vivo and in vitro Study

Angiogenesis, the formation of new blood vessels, stimulates tumor growth and spread by delivering oxygen and nutrients, and is a key component of metastasis. This work aimed to evaluate the anti-angiogenic properties of a new synthesized compound. Rat aorta angiogenesis assay was used to evaluate t...

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Veröffentlicht in:	Asian Pacific Journal of Cancer Prevention 2024-07, Vol.25 (7), p.2509-2513
Hauptverfasser:	Aldhalmi, Ahmed K, Sahib, Hayder B, Hassan, Omeed M, Mahmood, Ammar A Razzak, Tahtamouni, Lubna H
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Angiogenesis Inhibitors - pharmacology Animals Antineoplastic Agents - pharmacology Cell Proliferation - drug effects Human Umbilical Vein Endothelial Cells - drug effects Humans Hydrazines - pharmacology Lung Neoplasms - drug therapy Lung Neoplasms - pathology Male Neovascularization, Pathologic - drug therapy Neovascularization, Pathologic - pathology Rats Thioamides - chemistry Thioamides - pharmacology
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