Thrombin, unlike vasopressin, appears to stimulate two distinct guanine nucleotide regulatory proteins in human platelets

The thrombin-stimulated GTPase activity of human platelets was additive with respect to the GTPase stimulation effected by prostaglandin E1, but not with that stimulated by adrenaline, vasopressin and platelet-activating factor (PAF). Treatment of platelet membranes with pertussis toxin partially in...

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Veröffentlicht in:	Biochemical journal 1986-08, Vol.238 (1), p.109-113
Hauptverfasser:	Houslay, M D, Bojanic, D, Gawler, D, O'Hagan, S, Wilson, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylate Cyclase Toxin Adenylyl Cyclase Inhibitors ADP-Ribosylation Factors Blood Platelets - enzymology Blood Platelets - metabolism Cholera Toxin - pharmacology GTP Phosphohydrolases - metabolism GTP-Binding Proteins - blood Humans In Vitro Techniques Ligands Membrane Proteins - metabolism Pertussis Toxin Thrombin - pharmacology Vasopressins - pharmacology Virulence Factors, Bordetella - pharmacology
Online-Zugang:	Volltext
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