Lysosomes, but not mitochondria, accumulate iron and porphyrins in porphyria induced by hexachlorobenzene

In female rats with porphyria induced by hexachlorobenzene, the amounts of non-haem iron and porphyrins in liver mitochondrial fractions were increased almost 3-fold and greater than 500-fold respectively compared with that of untreated animals. A considerable fraction of both iron and porphyrins in...

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Veröffentlicht in:	Biochemical journal 1986-05, Vol.235 (3), p.671-675
1. Verfasser:	Tangeraas, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Centrifugation Chelating Agents Female Hexachlorobenzene Iron - metabolism Liver - metabolism Lysosomes - metabolism Mitochondria, Liver - metabolism Phenanthrolines Porphyrias - chemically induced Porphyrias - metabolism Porphyrins - metabolism Rats Rats, Inbred Strains
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