SwrA-mediated Multimerization of DegU and an Upstream Activation Sequence Enhance Flagellar Gene Expression in Bacillus subtilis

[Display omitted] •SwrA is a small protein that causes oligomerization of the response regulator DegU to increase DNA binding both in vivo and in vitro.•DegU binds upstream of the Pflache promoter but requires SwrA-induced oligomerization to activate transcription.•The Pflache promoter has an upstre...

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Veröffentlicht in:Journal of molecular biology 2024-02, Vol.436 (4), p.168419-168419, Article 168419
Hauptverfasser: Mishra, Ayushi, Hughes, Anna C., Amon, Jeremy D., Rudner, David Z., Wang, Xindan, Kearns, Daniel B.
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Sprache:eng
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