Distinct Mechanisms Underlie Boosted Polysaccharide-Specific IgG Responses Following Secondary Challenge with Intact Gram-Negative versus Gram-Positive Extracellular Bacteria

Priming of mice with intact, heat-killed cells of Gram-negative Neisseria meningitidis, capsular serogroup C (MenC) or Gram-positive group B Streptococcus, capsular type III (GBS-III) bacteria resulted in augmented serum polysaccharide (PS)-specific IgG titers following booster immunization. Inducti...

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Veröffentlicht in:	The Journal of immunology (1950) 2016-06, Vol.196 (11), p.4614-4621
Hauptverfasser:	Kar, Swagata, Arjunaraja, Swadhinya, Akkoyunlu, Mustafa, Pier, Gerald B, Snapper, Clifford M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - immunology Immunoglobulin G - immunology Mice Mice, Inbred BALB C Mice, Nude Neisseria meningitidis - classification Neisseria meningitidis - immunology Polysaccharides - immunology Streptococcus agalactiae - classification Streptococcus agalactiae - immunology
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