Sclerotic-Type Cutaneous Chronic Graft-Versus-Host Disease Exhibits Activation of T Helper 1 and OX40 Cytokines

Sclerotic-type cutaneous chronic graft-versus-host disease is a severe complication of allogeneic hematopoietic stem cell transplantation, with profound morbidity. A dearth of effective, targeted treatment options necessitates further investigation into the molecular mechanisms underlying this T-cel...

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Veröffentlicht in:	Journal of investigative dermatology 2024-03, Vol.144 (3), p.563-572.e9
Hauptverfasser:	Kim, Madeline, Renert-Yuval, Yael, Stepensky, Polina, Even-Or, Ehud, Zaidman, Irina, Fachler, Tahel, Neumark, Michal, Zamir, Mariana, NandyMazumdar, Monali, Gour, Digpal, Facheris, Paola, Carroll, Britta, Liu, Ying, Yu Ekey, Mitchelle L., Andrews, Elizabeth, Meariman, Marguerite, Angelov, Michael, Bose, Swaroop, Estrada, Yeriel D., Molho-Pessach, Vered, Guttman-Yassky, Emma
Format:	Artikel
Sprache:	eng
Schlagworte:	Bronchiolitis Obliterans Syndrome Child Cytokines - metabolism Dermatitis, Atopic - genetics Dermatitis, Atopic - pathology Endothelial Cells - metabolism Graft vs Host Disease - genetics Humans OX40 Ligand Skin Diseases Th2 Cells - metabolism Young Adult
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