RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines

Therapeutic targeting of dysregulated transcription has emerged as a promising strategy for the treatment of cancers, such as leukaemias. The therapeutic response to small molecule inhibitors of Bromodomain-Containing Proteins (BRD), such as BRD2 and BRD4, P300/cAMP-response element binding protein...

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Veröffentlicht in:	NAR cancer 2024-10, Vol.6 (4), p.zcae039
Hauptverfasser:	Todorovski, Izabela, Tsang, Mary-Jane, Feran, Breon, Fan, Zheng, Gadipally, Sreeja, Yoannidis, David, Kong, Isabella Y, Bjelosevic, Stefan, Rivera, Sarahi, Voulgaris, Olivia, Zethoven, Magnus, Hawkins, Edwin D, Simpson, Kaylene J, Arnau, Gisela Mir, Papenfuss, Anthony T, Johnstone, Ricky W, Vervoort, Stephin J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Gene Regulation, Chromatin, and Epigenetics
Online-Zugang:	Volltext
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