Coupled synthetic pathways improve the production of 3-hydroxypropionic acid in recombinant Escherichia coli strains

To improve the production of 3-HP with glucose as a substrate, the malonyl-CoA and propionyl-CoA pathways were coupled to regulate NADP /NADPH regeneration in the recombinant . The strain -AM that overexpressed the key enzymes of the malonyl-CoA pathway, acetyl CoA carboxylase (ACC) from and malonyl...

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Veröffentlicht in:Biotechnology Notes 2022-01, Vol.3, p.25-31
Hauptverfasser: Zhou, Dafeng, Quiroga-Sánchez, Diego Leandro, Zhang, Xuan, Chang, Yanhong, Luo, Hui
Format: Artikel
Sprache:eng
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