Daily Adequate Intake of Fruit and Vegetables and All-Cause, Cardiovascular Disease, and Cancer Mortalities in Malaysian Population: A Retrospective Cohort Study
We investigated the relationship between daily adequate FV intake and risk of all-cause, cardiovascular disease (CVD), and cancer mortalities among Malaysian adults. Data from a total of 18,211 Malaysian adults aged 18 years and above whom participated in the National Health and Morbidity Survey 201...
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description | We investigated the relationship between daily adequate FV intake and risk of all-cause, cardiovascular disease (CVD), and cancer mortalities among Malaysian adults.
Data from a total of 18,211 Malaysian adults aged 18 years and above whom participated in the National Health and Morbidity Survey 2011 were analyzed. The participants were followed up for approximately 11 years, and mortality data were ascertained through record linkages with the death registry from the Malaysian National Registration Department. Multiple Cox regression was applied to assess the association between daily adequate FV intake and risk of all-cause, CVD, and cancer mortalities, adjusting for sociodemographic, lifestyle, and health conditions.
During the follow-up period, we observed a total of 1809 all-cause, 374 CVD, and 216 cancer mortalities. No significant association between daily adequate FV intake with all-cause mortality (adjusted hazard ratio (aHR): 1.01, 95% confidence interval (CI: 0.79-1.31), CVD mortality (aHR: 0.91, 95% CI: 0.57-1.47), and cancer mortality (aHR: 1.27, 95% CI: 0.74-2.17) were observed, even after excluding deaths that occurred in the first two years of observation.
Further investigation on the type of FV intake and its preparation method with risk of mortality will provide a holistic insight into the causal relationship between FV intake and mortality. |
doi_str_mv | 10.3390/nu16183200 |
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Data from a total of 18,211 Malaysian adults aged 18 years and above whom participated in the National Health and Morbidity Survey 2011 were analyzed. The participants were followed up for approximately 11 years, and mortality data were ascertained through record linkages with the death registry from the Malaysian National Registration Department. Multiple Cox regression was applied to assess the association between daily adequate FV intake and risk of all-cause, CVD, and cancer mortalities, adjusting for sociodemographic, lifestyle, and health conditions.
During the follow-up period, we observed a total of 1809 all-cause, 374 CVD, and 216 cancer mortalities. No significant association between daily adequate FV intake with all-cause mortality (adjusted hazard ratio (aHR): 1.01, 95% confidence interval (CI: 0.79-1.31), CVD mortality (aHR: 0.91, 95% CI: 0.57-1.47), and cancer mortality (aHR: 1.27, 95% CI: 0.74-2.17) were observed, even after excluding deaths that occurred in the first two years of observation.
Further investigation on the type of FV intake and its preparation method with risk of mortality will provide a holistic insight into the causal relationship between FV intake and mortality.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu16183200</identifier><identifier>PMID: 39339800</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Adequate Intakes ; Adolescent ; Adult ; Aged ; Analysis ; Cancer ; Cardiovascular diseases ; Cardiovascular Diseases - mortality ; Cause of Death ; Chronic illnesses ; Cohort analysis ; cohort studies ; confidence interval ; Data collection ; death ; Diet ; Disease ; Ethnicity ; Female ; Food ; Fruit ; Fruits ; hazard ratio ; Health care ; Households ; Humans ; Hypertension ; lifestyle ; Lifestyles ; Malaysia ; Malaysia - epidemiology ; Male ; Middle Aged ; Mortality ; Neoplasms - mortality ; Nutrition ; Oncology, Experimental ; Patient outcomes ; Population ; Proportional Hazards Models ; regression analysis ; Retrospective Studies ; risk ; Risk Factors ; Sociodemographics ; Vegetables ; Vegetarianism ; Young Adult</subject><ispartof>Nutrients, 2024-09, Vol.16 (18), p.3200</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2024 by the authors. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c396t-d1ca62a2cb4a77a810b59c82153241449743d675646d7605b9e7293725cabcb3</cites><orcidid>0000-0002-6793-7055 ; 0000-0001-5846-2783 ; 0000-0003-1372-9549 ; 0000-0002-3019-1739</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435129/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435129/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39339800$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tan, Lay Kim</creatorcontrib><creatorcontrib>Zainuddin, Nabilah Hanis</creatorcontrib><creatorcontrib>Tohar, Najjah</creatorcontrib><creatorcontrib>Sanaudi, Ridwan</creatorcontrib><creatorcontrib>Cheah, Yong Kang</creatorcontrib><creatorcontrib>Omar, Mohd Azahadi</creatorcontrib><creatorcontrib>Kee, Chee Cheong</creatorcontrib><title>Daily Adequate Intake of Fruit and Vegetables and All-Cause, Cardiovascular Disease, and Cancer Mortalities in Malaysian Population: A Retrospective Cohort Study</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>We investigated the relationship between daily adequate FV intake and risk of all-cause, cardiovascular disease (CVD), and cancer mortalities among Malaysian adults.
Data from a total of 18,211 Malaysian adults aged 18 years and above whom participated in the National Health and Morbidity Survey 2011 were analyzed. The participants were followed up for approximately 11 years, and mortality data were ascertained through record linkages with the death registry from the Malaysian National Registration Department. Multiple Cox regression was applied to assess the association between daily adequate FV intake and risk of all-cause, CVD, and cancer mortalities, adjusting for sociodemographic, lifestyle, and health conditions.
During the follow-up period, we observed a total of 1809 all-cause, 374 CVD, and 216 cancer mortalities. No significant association between daily adequate FV intake with all-cause mortality (adjusted hazard ratio (aHR): 1.01, 95% confidence interval (CI: 0.79-1.31), CVD mortality (aHR: 0.91, 95% CI: 0.57-1.47), and cancer mortality (aHR: 1.27, 95% CI: 0.74-2.17) were observed, even after excluding deaths that occurred in the first two years of observation.
Further investigation on the type of FV intake and its preparation method with risk of mortality will provide a holistic insight into the causal relationship between FV intake and mortality.</description><subject>Adequate Intakes</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Analysis</subject><subject>Cancer</subject><subject>Cardiovascular diseases</subject><subject>Cardiovascular Diseases - mortality</subject><subject>Cause of Death</subject><subject>Chronic illnesses</subject><subject>Cohort analysis</subject><subject>cohort studies</subject><subject>confidence interval</subject><subject>Data collection</subject><subject>death</subject><subject>Diet</subject><subject>Disease</subject><subject>Ethnicity</subject><subject>Female</subject><subject>Food</subject><subject>Fruit</subject><subject>Fruits</subject><subject>hazard ratio</subject><subject>Health care</subject><subject>Households</subject><subject>Humans</subject><subject>Hypertension</subject><subject>lifestyle</subject><subject>Lifestyles</subject><subject>Malaysia</subject><subject>Malaysia - epidemiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Neoplasms - mortality</subject><subject>Nutrition</subject><subject>Oncology, Experimental</subject><subject>Patient outcomes</subject><subject>Population</subject><subject>Proportional Hazards Models</subject><subject>regression analysis</subject><subject>Retrospective Studies</subject><subject>risk</subject><subject>Risk Factors</subject><subject>Sociodemographics</subject><subject>Vegetables</subject><subject>Vegetarianism</subject><subject>Young Adult</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkl1rFDEUhgdRbFl74w-QgDcibs3HTLLjTVmmthZaFC3eDmcyZ7ep2WSbZBb25_hPm2lrP0QwuUhy8rwvh3NOUbxmdF-Imn50A5NsJjilz4pdThWfSlmK54_uO8VejJd0XIoqKV4WO6LO2hmlu8XvQzB2S-Y9Xg2QkJy4BL-Q-AU5CoNJBFxPfuISE3QW481zbu20gSHiB9JA6I3fQNSDhUAOTUQY4yPWgNMYyJkPCaxJJquNI2dgYRsNOPLNr7MoGe8-kTn5jin4uEadzAZJ4y-yjPxIQ799VbxYgI24d3dOivOjz-fNl-np1-OTZn461aKWadozDZID110JSsGM0a6q9YyzSvCSlWWtStFLVclS9krSqqtR8VooXmnodCcmxcGt7XroVthrdCmAbdfBrCBsWw-mffrjzEW79JuWsVJULFtNind3DsFfDRhTuzJRo7Xg0A-xFTmV3CieE_k_ymidPaXK6Nu_0Es_BJcrcUPJklesfKCWYLE1buFzjno0bee5FErJmRoz3P8HlXePK6O9w4XJ8SeC97cCnZsTAy7u68FoO45f-zB-GX7zuIL36J9hE9eBltOx</recordid><startdate>20240921</startdate><enddate>20240921</enddate><creator>Tan, Lay Kim</creator><creator>Zainuddin, Nabilah Hanis</creator><creator>Tohar, Najjah</creator><creator>Sanaudi, Ridwan</creator><creator>Cheah, Yong Kang</creator><creator>Omar, Mohd Azahadi</creator><creator>Kee, Chee Cheong</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6793-7055</orcidid><orcidid>https://orcid.org/0000-0001-5846-2783</orcidid><orcidid>https://orcid.org/0000-0003-1372-9549</orcidid><orcidid>https://orcid.org/0000-0002-3019-1739</orcidid></search><sort><creationdate>20240921</creationdate><title>Daily Adequate Intake of Fruit and Vegetables and All-Cause, Cardiovascular Disease, and Cancer Mortalities in Malaysian Population: A Retrospective Cohort Study</title><author>Tan, Lay Kim ; 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Data from a total of 18,211 Malaysian adults aged 18 years and above whom participated in the National Health and Morbidity Survey 2011 were analyzed. The participants were followed up for approximately 11 years, and mortality data were ascertained through record linkages with the death registry from the Malaysian National Registration Department. Multiple Cox regression was applied to assess the association between daily adequate FV intake and risk of all-cause, CVD, and cancer mortalities, adjusting for sociodemographic, lifestyle, and health conditions.
During the follow-up period, we observed a total of 1809 all-cause, 374 CVD, and 216 cancer mortalities. No significant association between daily adequate FV intake with all-cause mortality (adjusted hazard ratio (aHR): 1.01, 95% confidence interval (CI: 0.79-1.31), CVD mortality (aHR: 0.91, 95% CI: 0.57-1.47), and cancer mortality (aHR: 1.27, 95% CI: 0.74-2.17) were observed, even after excluding deaths that occurred in the first two years of observation.
Further investigation on the type of FV intake and its preparation method with risk of mortality will provide a holistic insight into the causal relationship between FV intake and mortality.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>39339800</pmid><doi>10.3390/nu16183200</doi><orcidid>https://orcid.org/0000-0002-6793-7055</orcidid><orcidid>https://orcid.org/0000-0001-5846-2783</orcidid><orcidid>https://orcid.org/0000-0003-1372-9549</orcidid><orcidid>https://orcid.org/0000-0002-3019-1739</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adequate Intakes Adolescent Adult Aged Analysis Cancer Cardiovascular diseases Cardiovascular Diseases - mortality Cause of Death Chronic illnesses Cohort analysis cohort studies confidence interval Data collection death Diet Disease Ethnicity Female Food Fruit Fruits hazard ratio Health care Households Humans Hypertension lifestyle Lifestyles Malaysia Malaysia - epidemiology Male Middle Aged Mortality Neoplasms - mortality Nutrition Oncology, Experimental Patient outcomes Population Proportional Hazards Models regression analysis Retrospective Studies risk Risk Factors Sociodemographics Vegetables Vegetarianism Young Adult |
title | Daily Adequate Intake of Fruit and Vegetables and All-Cause, Cardiovascular Disease, and Cancer Mortalities in Malaysian Population: A Retrospective Cohort Study |
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