Vitexin Mitigates Haloperidol-Induced Orofacial Dyskinesia in Rats through Activation of the Nrf2 Pathway

Vitexin (VTX), a C-glycosylated flavone found in various medicinal herbs, is known for its antioxidant, anti-inflammatory, and neuroprotective properties. This study investigated the protective effects of VTX against orofacial dyskinesia (OD) in rats, induced by haloperidol (HPD), along with the neu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2024-09, Vol.25 (18), p.10206
Hauptverfasser:	Chen, Shu-Mei, Wang, Mao-Hsien, Chang, Kuo-Chi, Fang, Chih-Hsiang, Lin, Yi-Wen, Tseng, Hsiang-Chien
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Antioxidants - pharmacology Antipsychotics Apigenin - pharmacology Apoptosis Apoptosis - drug effects Bioflavonoids Biperiden Care and treatment Causes of Central nervous system depressants Complications and side effects Corpus Striatum - drug effects Corpus Striatum - metabolism Cytochrome Cytokines Dyskinesia Dyskinesia, Drug-Induced - drug therapy Dyskinesia, Drug-Induced - metabolism Enzymes Ethylenediaminetetraacetic acid Flavones Flavonoids Haloperidol Haloperidol - adverse effects Haloperidol - pharmacology Health aspects Lipids Male Medicinal plants Medicine, Botanic Medicine, Herbal Neurodegeneration Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Neurotoxicity NF-E2-Related Factor 2 - metabolism Nitric oxide Oxidative stress Oxidative Stress - drug effects Physiological aspects Proteins Psychotropic drugs Rats Schizophrenia Signal Transduction - drug effects Tardive dyskinesia Transcription factors Tumor necrosis factor-TNF
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!