CHIR99021 and Brdu Are Critical in Chicken iPSC Reprogramming via Small-Molecule Screening

Induced pluripotent stem cells (iPSCs) reprogrammed from somatic cells into cells with most of the ESC (embryonic stem cell) characteristics show promise toward solving ethical problems currently facing stem cell research and eventually yield clinical grade pluripotent stem cells for therapies and r...

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Veröffentlicht in:	Genes 2024-09, Vol.15 (9), p.1206
Hauptverfasser:	Jin, Kai, Zhou, Jing, Wu, Gaoyuan, Li, Zeyu, Zhu, Xilin, Liang, Youchen, Li, Tingting, Chen, Guohong, Zuo, Qisheng, Niu, Yingjie, Song, Jiuzhou, Han, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascorbic acid Cell differentiation Cell Differentiation - drug effects Cell fate Cells, Cultured Cellular Reprogramming - drug effects Chick Embryo Chickens Disease DNA binding proteins Drug development Embryo cells Embryo fibroblasts Epigenetics Ethics Fibroblast growth factor 2 Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - metabolism Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - drug effects Induced Pluripotent Stem Cells - metabolism Medical research Pluripotency Poultry Pyridines - pharmacology Pyrimidines - pharmacology Regenerative medicine Signal transduction Small Molecule Libraries - pharmacology Somatic cells Stem cells Transcription factors Valproic acid Vitamin C
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