The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions’ (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study

Study Design Multicenter, international prospective study. Objective This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and resid...

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Veröffentlicht in:Global spine journal 2024-09, Vol.14 (7), p.1978-1989
Hauptverfasser: Jentzsch, Thorsten, Lewis, Stephen J., Oitment, Colby, Rienmüller, Anna, Martin, Allan R., Nielsen, Christopher J., Shear-Yashuv, Hananel, de Kleuver, Marinus, Qiu, Yong, Matsuyama, Yukihiro, Lenke, Lawrence G., Alanay, Ahmet, Pellisé-Urquiza, Ferran, Cheung, Kenneth M. C., Spruit, Maarten, Polly, David W., Sembrano, Jonathan N., Shaffrey, Christopher I., Smith, Justin S., Kelly, Michael P., Dahl, Benny, Berven, Sigurd H.
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container_end_page 1989
container_issue 7
container_start_page 1978
container_title Global spine journal
container_volume 14
creator Jentzsch, Thorsten
Lewis, Stephen J.
Oitment, Colby
Rienmüller, Anna
Martin, Allan R.
Nielsen, Christopher J.
Shear-Yashuv, Hananel
de Kleuver, Marinus
Qiu, Yong
Matsuyama, Yukihiro
Lenke, Lawrence G.
Alanay, Ahmet
Pellisé-Urquiza, Ferran
Cheung, Kenneth M. C.
Spruit, Maarten
Polly, David W.
Sembrano, Jonathan N.
Shaffrey, Christopher I.
Smith, Justin S.
Kelly, Michael P.
Dahl, Benny
Berven, Sigurd H.
description Study Design Multicenter, international prospective study. Objective This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. Methods As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. Results The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from .53 (SD .21) and 55.6 (SD 23.0) pre-operatively to .64 (SD .18) and 65.8 (SD 18.7) at 10 weeks, .74 (SD .18) and 72.7 (SD 18.1) at 12 months, and .73 (SD .20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was .22 (95% CI .15-.29). Conclusions The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was .22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively.
doi_str_mv 10.1177/21925682231162574
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C. ; Spruit, Maarten ; Polly, David W. ; Sembrano, Jonathan N. ; Shaffrey, Christopher I. ; Smith, Justin S. ; Kelly, Michael P. ; Dahl, Benny ; Berven, Sigurd H.</creator><creatorcontrib>Jentzsch, Thorsten ; Lewis, Stephen J. ; Oitment, Colby ; Rienmüller, Anna ; Martin, Allan R. ; Nielsen, Christopher J. ; Shear-Yashuv, Hananel ; de Kleuver, Marinus ; Qiu, Yong ; Matsuyama, Yukihiro ; Lenke, Lawrence G. ; Alanay, Ahmet ; Pellisé-Urquiza, Ferran ; Cheung, Kenneth M. C. ; Spruit, Maarten ; Polly, David W. ; Sembrano, Jonathan N. ; Shaffrey, Christopher I. ; Smith, Justin S. ; Kelly, Michael P. ; Dahl, Benny ; Berven, Sigurd H. ; AO Spine Knowledge Forum Deformity ; AO Spine Knowledge Forum Deformity</creatorcontrib><description>Study Design Multicenter, international prospective study. Objective This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. Methods As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. Results The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from .53 (SD .21) and 55.6 (SD 23.0) pre-operatively to .64 (SD .18) and 65.8 (SD 18.7) at 10 weeks, .74 (SD .18) and 72.7 (SD 18.1) at 12 months, and .73 (SD .20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was .22 (95% CI .15-.29). Conclusions The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was .22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively.</description><identifier>ISSN: 2192-5682</identifier><identifier>EISSN: 2192-5690</identifier><identifier>DOI: 10.1177/21925682231162574</identifier><identifier>PMID: 36943086</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Original ; Surgery</subject><ispartof>Global spine journal, 2024-09, Vol.14 (7), p.1978-1989</ispartof><rights>The Author(s) 2023</rights><rights>The Author(s) 2023. This work is licensed under the Creative Commons Attribution – Non-Commercial – No Derivatives License https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2023 2023 AO Spine, unless otherwise noted. Manuscript content on this site is licensed under Creative Commons Licenses</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c419t-ca3ae4de34f292318da3383a2cd9e9964085e2317b14b2ad99d3cc81a93d8e83</cites><orcidid>0000-0003-4202-6092 ; 0000-0001-6221-7406 ; 0000-0003-1351-9410 ; 0000-0002-6133-3314 ; 0000-0001-8304-0419 ; 0000-0002-9173-8443</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418680/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418680/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,21966,27853,27924,27925,44945,45333,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36943086$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jentzsch, Thorsten</creatorcontrib><creatorcontrib>Lewis, Stephen J.</creatorcontrib><creatorcontrib>Oitment, Colby</creatorcontrib><creatorcontrib>Rienmüller, Anna</creatorcontrib><creatorcontrib>Martin, Allan R.</creatorcontrib><creatorcontrib>Nielsen, Christopher J.</creatorcontrib><creatorcontrib>Shear-Yashuv, Hananel</creatorcontrib><creatorcontrib>de Kleuver, Marinus</creatorcontrib><creatorcontrib>Qiu, Yong</creatorcontrib><creatorcontrib>Matsuyama, Yukihiro</creatorcontrib><creatorcontrib>Lenke, Lawrence G.</creatorcontrib><creatorcontrib>Alanay, Ahmet</creatorcontrib><creatorcontrib>Pellisé-Urquiza, Ferran</creatorcontrib><creatorcontrib>Cheung, Kenneth M. C.</creatorcontrib><creatorcontrib>Spruit, Maarten</creatorcontrib><creatorcontrib>Polly, David W.</creatorcontrib><creatorcontrib>Sembrano, Jonathan N.</creatorcontrib><creatorcontrib>Shaffrey, Christopher I.</creatorcontrib><creatorcontrib>Smith, Justin S.</creatorcontrib><creatorcontrib>Kelly, Michael P.</creatorcontrib><creatorcontrib>Dahl, Benny</creatorcontrib><creatorcontrib>Berven, Sigurd H.</creatorcontrib><creatorcontrib>AO Spine Knowledge Forum Deformity</creatorcontrib><creatorcontrib>AO Spine Knowledge Forum Deformity</creatorcontrib><title>The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions’ (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study</title><title>Global spine journal</title><addtitle>Global Spine J</addtitle><description>Study Design Multicenter, international prospective study. Objective This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. Methods As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. Results The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from .53 (SD .21) and 55.6 (SD 23.0) pre-operatively to .64 (SD .18) and 65.8 (SD 18.7) at 10 weeks, .74 (SD .18) and 72.7 (SD 18.1) at 12 months, and .73 (SD .20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was .22 (95% CI .15-.29). Conclusions The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was .22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively.</description><subject>Original</subject><subject>Surgery</subject><issn>2192-5682</issn><issn>2192-5690</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1kttuEzEQhlcIRKvSB-AGWeKmSN3iwx5sblDVBKhUVEJyv3LWs6krx07tdaS94zV4G56FJ8GrhHASvrE1_uebf0aTZc8JviCkrl9TImhZcUoZIRUt6-JRdjzG8rIS-PHhzelRdhrCPU6nojUj9Gl2xCpRMMyr4-zb4g7Qte1MBNsCch36GE2vDWzBoPlGW2nQBDrn17of0Dz6FfgBOYv6lDeN3s2cQSWa6DXYoJ0N3798RWfTWV5OXqFZhNCnoJXaA5JWoc8QtALb64Sd97KPAek9yyjwZniDLtEn78IG2l5v4RzdLgP4rRwx0pzv3LWJAD4BohqeZU86aQKc7u-TbPFuurj6kN_cvr--urzJ24KIPm8lk1AoYEVHRRoZV5IxziRtlQAhqgLzElK8XpJiSaUSQrG25UQKpjhwdpK93WE3cbkGNTrw0jQbr9fSD42Tuvnzx-q7ZuW2DSEF4RXHiXC2J3j3MA6mWevQgjHSgouhoTVPxqoK10n68i_pvYs-9R8aRnBdYlLTIqnITtWmeQUP3cENwc24Is0_K5JyXvzexiHj50IkwcVOEOQKfpX9P_EHYjLHBg</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Jentzsch, Thorsten</creator><creator>Lewis, Stephen J.</creator><creator>Oitment, Colby</creator><creator>Rienmüller, Anna</creator><creator>Martin, Allan R.</creator><creator>Nielsen, Christopher J.</creator><creator>Shear-Yashuv, Hananel</creator><creator>de Kleuver, Marinus</creator><creator>Qiu, Yong</creator><creator>Matsuyama, Yukihiro</creator><creator>Lenke, Lawrence G.</creator><creator>Alanay, Ahmet</creator><creator>Pellisé-Urquiza, Ferran</creator><creator>Cheung, Kenneth M. 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C.</au><au>Spruit, Maarten</au><au>Polly, David W.</au><au>Sembrano, Jonathan N.</au><au>Shaffrey, Christopher I.</au><au>Smith, Justin S.</au><au>Kelly, Michael P.</au><au>Dahl, Benny</au><au>Berven, Sigurd H.</au><aucorp>AO Spine Knowledge Forum Deformity</aucorp><aucorp>AO Spine Knowledge Forum Deformity</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions’ (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study</atitle><jtitle>Global spine journal</jtitle><addtitle>Global Spine J</addtitle><date>2024-09-01</date><risdate>2024</risdate><volume>14</volume><issue>7</issue><spage>1978</spage><epage>1989</epage><pages>1978-1989</pages><issn>2192-5682</issn><eissn>2192-5690</eissn><abstract>Study Design Multicenter, international prospective study. Objective This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. Methods As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. Results The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from .53 (SD .21) and 55.6 (SD 23.0) pre-operatively to .64 (SD .18) and 65.8 (SD 18.7) at 10 weeks, .74 (SD .18) and 72.7 (SD 18.1) at 12 months, and .73 (SD .20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was .22 (95% CI .15-.29). Conclusions The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was .22. 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subjects Original
Surgery
title The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions’ (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study
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