Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ

The mitochondrial single-stranded DNA (ssDNA) binding protein, mtSSB or SSBP1, binds to ssDNA to prevent secondary structures of DNA that could impede downstream replication or repair processes. Clinical mutations in the SSBP1 gene have been linked to a range of mitochondrial disorders affecting nea...

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Veröffentlicht in:	Nucleic acids research 2024-08, Vol.52 (17), p.10329-10340
Hauptverfasser:	Riccio, Amanda A, Bouvette, Jonathan, Pedersen, Lars C, Somai, Shruti, Dutcher, Robert C, Borgnia, Mario J, Copeland, William C
Format:	Artikel
Sprache:	eng
Schlagworte:	Genome Integrity, Repair and
Online-Zugang:	Volltext
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