Multi-omics analysis of SIV-specific CD8+ T cells in multiple anatomical sites

CD8+ T cells exert immunological pressure against immunodeficiency lentiviruses. In previous studies, we examined the TCR repertoire of CD8+ T cells specific for a single SIV immunodominant epitope, Gag-CM9, throughout SIV infection or after vaccination, and across multiple anatomic sites. We identi...

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Veröffentlicht in:	PLoS pathogens 2024-09, Vol.20 (9), p.e1012545
Hauptverfasser:	Simpson, Jennifer, Dulek, Brittany, Schaughency, Paul, Brenchley, Jason M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biology and life sciences CD8-Positive T-Lymphocytes - immunology Macaca mulatta Medicine and health sciences Multiomics Receptors, Antigen, T-Cell - immunology Research and Analysis Methods Simian Acquired Immunodeficiency Syndrome - immunology Simian Acquired Immunodeficiency Syndrome - virology Simian Immunodeficiency Virus - immunology
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