Risk factors for Helicobacter pylori infection in children with gastrointestinal symptoms in Vietnam
•A total of 81.3% of children with gastrointestinal symptoms tested positive for Helicobacter pylori.•Having family members with a history of H. pylori infection increased the risk of infection.•Handwashing with soap is associated with a lower risk of H. pylori infection. To investigate the prevalen...
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| Veröffentlicht in: | IJID regions 2024-09, Vol.12, p.100426, Article 100426 |
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| creator | Nguyen Le, Cam Anh Duong, Khanh Linh Bui, Duc Manh Le, Kieu Dung Dang, Khanh Linh Nguyen, Trung Kien Gautret, Philippe Hoang, Van Thuan Dao, Thi Loi |
| description | •A total of 81.3% of children with gastrointestinal symptoms tested positive for Helicobacter pylori.•Having family members with a history of H. pylori infection increased the risk of infection.•Handwashing with soap is associated with a lower risk of H. pylori infection.
To investigate the prevalence and risk factors associated with Helicobacter pylori infection in Vietnamese children.
Children under 16 years old with gastrointestinal symptoms underwent esophagogastroduodenoscopy and H. pylori infection was diagnosed using rapid urease test.
A total of 246 children with gastrointestinal symptoms were included. The mean age was 8.4 ± 2.6 years. A total 81.3% tested positive for H. pylori. Children infected with H. pylori had a lower rate of nausea but a higher rate of lesions in the duodenal bulb and nodular lesions than children without H. pylori infection (26.5% vs 45.6%, P |
| doi_str_mv | 10.1016/j.ijregi.2024.100426 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11408016</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S2772707624000973</els_id><sourcerecordid>3106736515</sourcerecordid><originalsourceid>FETCH-LOGICAL-c297t-67206c896486c0c9396986f09d959ac17debe38f5802b1640f5db712c28b3e613</originalsourceid><addsrcrecordid>eNp9kU1vFDEMhkcIRKvSf4BQjlx2m4-ZfFxAqIIWqRISAq5RJuPZ9TKTLEm2aP89WU2pyoWTLef169hP07xmdM0ok1e7Ne4SbHDNKW9ribZcPmvOuVJ8paiSz5_kZ81lzjtKKVempYK_bM6E4abTQp83w1fMP8nofIkpkzEmcgsT-tjXCiSyP04xIcEwgi8YQ82I3-I0JAjkN5Yt2bhcUsRQIBcMbiL5OO9LnPNJ-gOhBDe_al6Mbspw-RAvmu-fPn67vl3dfbn5fP3hbuW5UWUlFafSayNbLT31RhhptBypGUxnnGdqgB6EHjtNec9kS8du6BXjnutegGTionm_-O4P_QyDh1CSm-w-4ezS0UaH9t-XgFu7ifeWsZbqetfq8PbBIcVfh7qSnTF7mCYXIB6yFYxKJWTHuiptF6lPMecE4-McRu0Jkt3ZBZI9QbILpNr25ukfH5v-IqmCd4sA6qXuEZLNHiF4GDBVCHaI-P8JfwChUaaj</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3106736515</pqid></control><display><type>article</type><title>Risk factors for Helicobacter pylori infection in children with gastrointestinal symptoms in Vietnam</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Nguyen Le, Cam Anh ; Duong, Khanh Linh ; Bui, Duc Manh ; Le, Kieu Dung ; Dang, Khanh Linh ; Nguyen, Trung Kien ; Gautret, Philippe ; Hoang, Van Thuan ; Dao, Thi Loi</creator><creatorcontrib>Nguyen Le, Cam Anh ; Duong, Khanh Linh ; Bui, Duc Manh ; Le, Kieu Dung ; Dang, Khanh Linh ; Nguyen, Trung Kien ; Gautret, Philippe ; Hoang, Van Thuan ; Dao, Thi Loi</creatorcontrib><description>•A total of 81.3% of children with gastrointestinal symptoms tested positive for Helicobacter pylori.•Having family members with a history of H. pylori infection increased the risk of infection.•Handwashing with soap is associated with a lower risk of H. pylori infection.
To investigate the prevalence and risk factors associated with Helicobacter pylori infection in Vietnamese children.
Children under 16 years old with gastrointestinal symptoms underwent esophagogastroduodenoscopy and H. pylori infection was diagnosed using rapid urease test.
A total of 246 children with gastrointestinal symptoms were included. The mean age was 8.4 ± 2.6 years. A total 81.3% tested positive for H. pylori. Children infected with H. pylori had a lower rate of nausea but a higher rate of lesions in the duodenal bulb and nodular lesions than children without H. pylori infection (26.5% vs 45.6%, P <0.01; 40.0% vs 23.9%; P = 0.04; and 68.5% vs 30.3%, P <0.0001, respectively). Compared with children aged under 5 years, children aged 11 years and older were four times more likely to be infected with H. pylori, with odds ratio (OR) 3.50, 95% confidence interval (CI) 1.07-11.39, P = 0.04. Washing hands with soap was associated with a reduced risk of H. pylori infection by three times (OR 0.35, 95% CI 0.17-0.69, P = 0.002). Children living in a family where members had a history of H. pylori infection were nine times more likely to be infected with H. pylori (OR 8.87, 95% CI 1.15-68.45, P = 0.04).
The prevalence of H. pylori infection in Vietnamese children with gastroenteritis is high. Our results identified several risk factors and emphasize the role of handwashing with soap before eating and after using the toilet in reducing the risk of H. pylori infection in children.</description><identifier>ISSN: 2772-7076</identifier><identifier>EISSN: 2772-7076</identifier><identifier>DOI: 10.1016/j.ijregi.2024.100426</identifier><identifier>PMID: 39295838</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Children ; Esophagogastroduodenoscopy ; Gastroenteritis ; H. pylori ; Original Report ; Risk factor</subject><ispartof>IJID regions, 2024-09, Vol.12, p.100426, Article 100426</ispartof><rights>2024 The Author(s)</rights><rights>2024 The Author(s).</rights><rights>2024 The Author(s) 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c297t-67206c896486c0c9396986f09d959ac17debe38f5802b1640f5db712c28b3e613</cites><orcidid>0000-0003-1369-8615 ; 0009-0007-7750-4572 ; 0009-0001-7647-3483 ; 0009-0009-4101-4058 ; 0000-0002-1664-958X ; 0000-0001-7129-3785</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11408016/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11408016/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39295838$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nguyen Le, Cam Anh</creatorcontrib><creatorcontrib>Duong, Khanh Linh</creatorcontrib><creatorcontrib>Bui, Duc Manh</creatorcontrib><creatorcontrib>Le, Kieu Dung</creatorcontrib><creatorcontrib>Dang, Khanh Linh</creatorcontrib><creatorcontrib>Nguyen, Trung Kien</creatorcontrib><creatorcontrib>Gautret, Philippe</creatorcontrib><creatorcontrib>Hoang, Van Thuan</creatorcontrib><creatorcontrib>Dao, Thi Loi</creatorcontrib><title>Risk factors for Helicobacter pylori infection in children with gastrointestinal symptoms in Vietnam</title><title>IJID regions</title><addtitle>IJID Reg</addtitle><description>•A total of 81.3% of children with gastrointestinal symptoms tested positive for Helicobacter pylori.•Having family members with a history of H. pylori infection increased the risk of infection.•Handwashing with soap is associated with a lower risk of H. pylori infection.
To investigate the prevalence and risk factors associated with Helicobacter pylori infection in Vietnamese children.
Children under 16 years old with gastrointestinal symptoms underwent esophagogastroduodenoscopy and H. pylori infection was diagnosed using rapid urease test.
A total of 246 children with gastrointestinal symptoms were included. The mean age was 8.4 ± 2.6 years. A total 81.3% tested positive for H. pylori. Children infected with H. pylori had a lower rate of nausea but a higher rate of lesions in the duodenal bulb and nodular lesions than children without H. pylori infection (26.5% vs 45.6%, P <0.01; 40.0% vs 23.9%; P = 0.04; and 68.5% vs 30.3%, P <0.0001, respectively). Compared with children aged under 5 years, children aged 11 years and older were four times more likely to be infected with H. pylori, with odds ratio (OR) 3.50, 95% confidence interval (CI) 1.07-11.39, P = 0.04. Washing hands with soap was associated with a reduced risk of H. pylori infection by three times (OR 0.35, 95% CI 0.17-0.69, P = 0.002). Children living in a family where members had a history of H. pylori infection were nine times more likely to be infected with H. pylori (OR 8.87, 95% CI 1.15-68.45, P = 0.04).
The prevalence of H. pylori infection in Vietnamese children with gastroenteritis is high. Our results identified several risk factors and emphasize the role of handwashing with soap before eating and after using the toilet in reducing the risk of H. pylori infection in children.</description><subject>Children</subject><subject>Esophagogastroduodenoscopy</subject><subject>Gastroenteritis</subject><subject>H. pylori</subject><subject>Original Report</subject><subject>Risk factor</subject><issn>2772-7076</issn><issn>2772-7076</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kU1vFDEMhkcIRKvSf4BQjlx2m4-ZfFxAqIIWqRISAq5RJuPZ9TKTLEm2aP89WU2pyoWTLef169hP07xmdM0ok1e7Ne4SbHDNKW9ribZcPmvOuVJ8paiSz5_kZ81lzjtKKVempYK_bM6E4abTQp83w1fMP8nofIkpkzEmcgsT-tjXCiSyP04xIcEwgi8YQ82I3-I0JAjkN5Yt2bhcUsRQIBcMbiL5OO9LnPNJ-gOhBDe_al6Mbspw-RAvmu-fPn67vl3dfbn5fP3hbuW5UWUlFafSayNbLT31RhhptBypGUxnnGdqgB6EHjtNec9kS8du6BXjnutegGTionm_-O4P_QyDh1CSm-w-4ezS0UaH9t-XgFu7ifeWsZbqetfq8PbBIcVfh7qSnTF7mCYXIB6yFYxKJWTHuiptF6lPMecE4-McRu0Jkt3ZBZI9QbILpNr25ukfH5v-IqmCd4sA6qXuEZLNHiF4GDBVCHaI-P8JfwChUaaj</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Nguyen Le, Cam Anh</creator><creator>Duong, Khanh Linh</creator><creator>Bui, Duc Manh</creator><creator>Le, Kieu Dung</creator><creator>Dang, Khanh Linh</creator><creator>Nguyen, Trung Kien</creator><creator>Gautret, Philippe</creator><creator>Hoang, Van Thuan</creator><creator>Dao, Thi Loi</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-1369-8615</orcidid><orcidid>https://orcid.org/0009-0007-7750-4572</orcidid><orcidid>https://orcid.org/0009-0001-7647-3483</orcidid><orcidid>https://orcid.org/0009-0009-4101-4058</orcidid><orcidid>https://orcid.org/0000-0002-1664-958X</orcidid><orcidid>https://orcid.org/0000-0001-7129-3785</orcidid></search><sort><creationdate>20240901</creationdate><title>Risk factors for Helicobacter pylori infection in children with gastrointestinal symptoms in Vietnam</title><author>Nguyen Le, Cam Anh ; Duong, Khanh Linh ; Bui, Duc Manh ; Le, Kieu Dung ; Dang, Khanh Linh ; Nguyen, Trung Kien ; Gautret, Philippe ; Hoang, Van Thuan ; Dao, Thi Loi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c297t-67206c896486c0c9396986f09d959ac17debe38f5802b1640f5db712c28b3e613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Children</topic><topic>Esophagogastroduodenoscopy</topic><topic>Gastroenteritis</topic><topic>H. pylori</topic><topic>Original Report</topic><topic>Risk factor</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nguyen Le, Cam Anh</creatorcontrib><creatorcontrib>Duong, Khanh Linh</creatorcontrib><creatorcontrib>Bui, Duc Manh</creatorcontrib><creatorcontrib>Le, Kieu Dung</creatorcontrib><creatorcontrib>Dang, Khanh Linh</creatorcontrib><creatorcontrib>Nguyen, Trung Kien</creatorcontrib><creatorcontrib>Gautret, Philippe</creatorcontrib><creatorcontrib>Hoang, Van Thuan</creatorcontrib><creatorcontrib>Dao, Thi Loi</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>IJID regions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nguyen Le, Cam Anh</au><au>Duong, Khanh Linh</au><au>Bui, Duc Manh</au><au>Le, Kieu Dung</au><au>Dang, Khanh Linh</au><au>Nguyen, Trung Kien</au><au>Gautret, Philippe</au><au>Hoang, Van Thuan</au><au>Dao, Thi Loi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk factors for Helicobacter pylori infection in children with gastrointestinal symptoms in Vietnam</atitle><jtitle>IJID regions</jtitle><addtitle>IJID Reg</addtitle><date>2024-09-01</date><risdate>2024</risdate><volume>12</volume><spage>100426</spage><pages>100426-</pages><artnum>100426</artnum><issn>2772-7076</issn><eissn>2772-7076</eissn><abstract>•A total of 81.3% of children with gastrointestinal symptoms tested positive for Helicobacter pylori.•Having family members with a history of H. pylori infection increased the risk of infection.•Handwashing with soap is associated with a lower risk of H. pylori infection.
To investigate the prevalence and risk factors associated with Helicobacter pylori infection in Vietnamese children.
Children under 16 years old with gastrointestinal symptoms underwent esophagogastroduodenoscopy and H. pylori infection was diagnosed using rapid urease test.
A total of 246 children with gastrointestinal symptoms were included. The mean age was 8.4 ± 2.6 years. A total 81.3% tested positive for H. pylori. Children infected with H. pylori had a lower rate of nausea but a higher rate of lesions in the duodenal bulb and nodular lesions than children without H. pylori infection (26.5% vs 45.6%, P <0.01; 40.0% vs 23.9%; P = 0.04; and 68.5% vs 30.3%, P <0.0001, respectively). Compared with children aged under 5 years, children aged 11 years and older were four times more likely to be infected with H. pylori, with odds ratio (OR) 3.50, 95% confidence interval (CI) 1.07-11.39, P = 0.04. Washing hands with soap was associated with a reduced risk of H. pylori infection by three times (OR 0.35, 95% CI 0.17-0.69, P = 0.002). Children living in a family where members had a history of H. pylori infection were nine times more likely to be infected with H. pylori (OR 8.87, 95% CI 1.15-68.45, P = 0.04).
The prevalence of H. pylori infection in Vietnamese children with gastroenteritis is high. Our results identified several risk factors and emphasize the role of handwashing with soap before eating and after using the toilet in reducing the risk of H. pylori infection in children.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>39295838</pmid><doi>10.1016/j.ijregi.2024.100426</doi><orcidid>https://orcid.org/0000-0003-1369-8615</orcidid><orcidid>https://orcid.org/0009-0007-7750-4572</orcidid><orcidid>https://orcid.org/0009-0001-7647-3483</orcidid><orcidid>https://orcid.org/0009-0009-4101-4058</orcidid><orcidid>https://orcid.org/0000-0002-1664-958X</orcidid><orcidid>https://orcid.org/0000-0001-7129-3785</orcidid><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Children Esophagogastroduodenoscopy Gastroenteritis H. pylori Original Report Risk factor |
| title | Risk factors for Helicobacter pylori infection in children with gastrointestinal symptoms in Vietnam |
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