Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci

Smoking is a leading cause of preventable morbidity and mortality. Smoking is heritable, and genome-wide association studies (GWASs) of smoking behaviors have identified hundreds of significant loci. Most GWAS-identified variants are noncoding with unknown neurobiological effects. We used genome-wid...

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Veröffentlicht in:Neuropsychopharmacology (New York, N.Y.) N.Y.), 2024-06, Vol.49 (11), p.1749-1757
Hauptverfasser: Carnes, Megan Ulmer, Quach, Bryan C, Zhou, Linran, Han, Shizhong, Tao, Ran, Mandal, Meisha, Deep-Soboslay, Amy, Marks, Jesse A, Page, Grier P, Maher, Brion S, Jaffe, Andrew E, Won, Hyejung, Bierut, Laura J, Hyde, Thomas M, Kleinman, Joel E, Johnson, Eric O, Hancock, Dana B
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Sprache:eng
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