Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas
Endoscopic treatment of superficial pharyngeal carcinomas includes endoscopic submucosal dissection (ESD; usually performed by endoscopists), and endoscopic laryngo-pharyngeal surgery (ELPS; primarily performed by otolaryngologists). Few studies have compared the efficacy of the two techniques in tr...
Gespeichert in:
| Veröffentlicht in: | DEN open 2025-04, Vol.5 (1), p.e70003 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1 |
| container_start_page | e70003 |
| container_title | DEN open |
| container_volume | 5 |
| creator | Fukuhara, Motomitsu Urabe, Yuji Nakamura, Takeo Ishibashi, Kazuki Konishi, Hirona Mizuno, Junichi Takasago, Takeshi Tanaka, Hidenori Tsuboi, Akiyoshi Yamashita, Ken Hiyama, Yuichi Takigawa, Hidehiko Kotachi, Takahiro Yuge, Ryo Ishikawa, Akira Taruya, Takayuki Ueda, Tsutomu Takeno, Sachio Oka, Shiro |
| description | Endoscopic treatment of superficial pharyngeal carcinomas includes endoscopic submucosal dissection (ESD; usually performed by endoscopists), and endoscopic laryngo-pharyngeal surgery (ELPS; primarily performed by otolaryngologists). Few studies have compared the efficacy of the two techniques in treating superficial pharyngeal carcinomas. In this study, we compared the outcomes of these two techniques to determine the advantages.
We retrospectively examined the short- and long-term outcomes of 93 consecutive patients with superficial pharyngeal carcinoma who either underwent an ESD or ELPS between August 2008 and December 2021.
There were 35 lesions among 29 patients and 93 lesions among 71 patients in the ESD and ELPS groups, respectively. The ELPS group had a significantly shorter procedure time (121.2 ± 97.4 min vs. 54.7 ± 40.2 min, p |
| doi_str_mv | 10.1002/deo2.70003 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11391100</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3104528214</sourcerecordid><originalsourceid>FETCH-LOGICAL-c268t-e67af039999957948ac54f72aa5fc5acf73ad2447236c5fc38e00cf902588883</originalsourceid><addsrcrecordid>eNpVkctuFDEQRS0EIlHIhg9AXiKkDn70c4XQCAhSJDbZW467PGPU7Wpc7qD5qXwjnslDQ21cKh_fqvJl7L0UV1II9XkEVFedEEK_YueqHVRVt2J4fZKfsUui34VQjdSyUW_ZmR5U28uuPmcPG5wXm2wO98BttNOegDh6TjtMuSqlkU8Yt1WGNHNcs8O5AHeQ_wJEDnFEcrgEx2m9m1eHZCc-BiJwOWA8vj-BJpv2cYvVsjsmUGBa0xbSnntMJV8g-eBCqZ8gziYXIs6W3rE33k4El0_nBbv9_u12c13d_Prxc_P1pnJlsVxB21kv9HCIphvq3rqm9p2ytvGusc532o6qrjulW1dKugchnB_KF_Ul9AX78ii7lKVgdBBzspNZUpjLUAZtMP_fxLAzW7w3UupBFl-KwscnhYR_VqBs5kAOpslGwJWMlqJuVK9kXdBPj6hLSJTAv_SRwhw8NgePzdHjAn84newFfXZU_wO-Gah7</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3104528214</pqid></control><display><type>article</type><title>Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas</title><source>Wiley Online Library Open Access</source><source>DOAJ Directory of Open Access Journals</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Fukuhara, Motomitsu ; Urabe, Yuji ; Nakamura, Takeo ; Ishibashi, Kazuki ; Konishi, Hirona ; Mizuno, Junichi ; Takasago, Takeshi ; Tanaka, Hidenori ; Tsuboi, Akiyoshi ; Yamashita, Ken ; Hiyama, Yuichi ; Takigawa, Hidehiko ; Kotachi, Takahiro ; Yuge, Ryo ; Ishikawa, Akira ; Taruya, Takayuki ; Ueda, Tsutomu ; Takeno, Sachio ; Oka, Shiro</creator><creatorcontrib>Fukuhara, Motomitsu ; Urabe, Yuji ; Nakamura, Takeo ; Ishibashi, Kazuki ; Konishi, Hirona ; Mizuno, Junichi ; Takasago, Takeshi ; Tanaka, Hidenori ; Tsuboi, Akiyoshi ; Yamashita, Ken ; Hiyama, Yuichi ; Takigawa, Hidehiko ; Kotachi, Takahiro ; Yuge, Ryo ; Ishikawa, Akira ; Taruya, Takayuki ; Ueda, Tsutomu ; Takeno, Sachio ; Oka, Shiro</creatorcontrib><description>Endoscopic treatment of superficial pharyngeal carcinomas includes endoscopic submucosal dissection (ESD; usually performed by endoscopists), and endoscopic laryngo-pharyngeal surgery (ELPS; primarily performed by otolaryngologists). Few studies have compared the efficacy of the two techniques in treating superficial pharyngeal carcinomas. In this study, we compared the outcomes of these two techniques to determine the advantages.
We retrospectively examined the short- and long-term outcomes of 93 consecutive patients with superficial pharyngeal carcinoma who either underwent an ESD or ELPS between August 2008 and December 2021.
There were 35 lesions among 29 patients and 93 lesions among 71 patients in the ESD and ELPS groups, respectively. The ELPS group had a significantly shorter procedure time (121.2 ± 97.4 min vs. 54.7 ± 40.2 min, p<0.01), greater procedure speed (0.10 ± 0.06 min/min vs. 0.30 ± 0.23 min/min, p<0.01), and less laryngeal edema than that of the ESD group. There were no significant differences in the 3-year overall, relapse-free, or disease-specific survival rates between the two groups. Intervention with ESD during ELPS was most commonly required when it was difficult to secure the visual field.
There were no differences in batch resection rates or long-term prognoses between the two groups; nevertheless, the ELPS group had a shorter treatment time and less laryngeal edema than the ESD group. However, the treatment of narrow areas, such as the esophageal inlet patch, is a technical limitation of ELPS; thus, ELPS should be combined with ESD techniques.</description><identifier>ISSN: 2692-4609</identifier><identifier>EISSN: 2692-4609</identifier><identifier>DOI: 10.1002/deo2.70003</identifier><identifier>PMID: 39268174</identifier><language>eng</language><publisher>Australia: John Wiley and Sons Inc</publisher><subject>Original</subject><ispartof>DEN open, 2025-04, Vol.5 (1), p.e70003</ispartof><rights>2024 The Author(s). DEN Open published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.</rights><rights>2024 The Author(s). published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c268t-e67af039999957948ac54f72aa5fc5acf73ad2447236c5fc38e00cf902588883</cites><orcidid>0000-0003-4154-658X ; 0000-0002-1652-0743 ; 0009-0009-9851-8564 ; 0000-0002-1528-1939 ; 0000-0002-3646-5796</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391100/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391100/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39268174$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fukuhara, Motomitsu</creatorcontrib><creatorcontrib>Urabe, Yuji</creatorcontrib><creatorcontrib>Nakamura, Takeo</creatorcontrib><creatorcontrib>Ishibashi, Kazuki</creatorcontrib><creatorcontrib>Konishi, Hirona</creatorcontrib><creatorcontrib>Mizuno, Junichi</creatorcontrib><creatorcontrib>Takasago, Takeshi</creatorcontrib><creatorcontrib>Tanaka, Hidenori</creatorcontrib><creatorcontrib>Tsuboi, Akiyoshi</creatorcontrib><creatorcontrib>Yamashita, Ken</creatorcontrib><creatorcontrib>Hiyama, Yuichi</creatorcontrib><creatorcontrib>Takigawa, Hidehiko</creatorcontrib><creatorcontrib>Kotachi, Takahiro</creatorcontrib><creatorcontrib>Yuge, Ryo</creatorcontrib><creatorcontrib>Ishikawa, Akira</creatorcontrib><creatorcontrib>Taruya, Takayuki</creatorcontrib><creatorcontrib>Ueda, Tsutomu</creatorcontrib><creatorcontrib>Takeno, Sachio</creatorcontrib><creatorcontrib>Oka, Shiro</creatorcontrib><title>Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas</title><title>DEN open</title><addtitle>DEN Open</addtitle><description>Endoscopic treatment of superficial pharyngeal carcinomas includes endoscopic submucosal dissection (ESD; usually performed by endoscopists), and endoscopic laryngo-pharyngeal surgery (ELPS; primarily performed by otolaryngologists). Few studies have compared the efficacy of the two techniques in treating superficial pharyngeal carcinomas. In this study, we compared the outcomes of these two techniques to determine the advantages.
We retrospectively examined the short- and long-term outcomes of 93 consecutive patients with superficial pharyngeal carcinoma who either underwent an ESD or ELPS between August 2008 and December 2021.
There were 35 lesions among 29 patients and 93 lesions among 71 patients in the ESD and ELPS groups, respectively. The ELPS group had a significantly shorter procedure time (121.2 ± 97.4 min vs. 54.7 ± 40.2 min, p<0.01), greater procedure speed (0.10 ± 0.06 min/min vs. 0.30 ± 0.23 min/min, p<0.01), and less laryngeal edema than that of the ESD group. There were no significant differences in the 3-year overall, relapse-free, or disease-specific survival rates between the two groups. Intervention with ESD during ELPS was most commonly required when it was difficult to secure the visual field.
There were no differences in batch resection rates or long-term prognoses between the two groups; nevertheless, the ELPS group had a shorter treatment time and less laryngeal edema than the ESD group. However, the treatment of narrow areas, such as the esophageal inlet patch, is a technical limitation of ELPS; thus, ELPS should be combined with ESD techniques.</description><subject>Original</subject><issn>2692-4609</issn><issn>2692-4609</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><recordid>eNpVkctuFDEQRS0EIlHIhg9AXiKkDn70c4XQCAhSJDbZW467PGPU7Wpc7qD5qXwjnslDQ21cKh_fqvJl7L0UV1II9XkEVFedEEK_YueqHVRVt2J4fZKfsUui34VQjdSyUW_ZmR5U28uuPmcPG5wXm2wO98BttNOegDh6TjtMuSqlkU8Yt1WGNHNcs8O5AHeQ_wJEDnFEcrgEx2m9m1eHZCc-BiJwOWA8vj-BJpv2cYvVsjsmUGBa0xbSnntMJV8g-eBCqZ8gziYXIs6W3rE33k4El0_nBbv9_u12c13d_Prxc_P1pnJlsVxB21kv9HCIphvq3rqm9p2ytvGusc532o6qrjulW1dKugchnB_KF_Ul9AX78ii7lKVgdBBzspNZUpjLUAZtMP_fxLAzW7w3UupBFl-KwscnhYR_VqBs5kAOpslGwJWMlqJuVK9kXdBPj6hLSJTAv_SRwhw8NgePzdHjAn84newFfXZU_wO-Gah7</recordid><startdate>20250401</startdate><enddate>20250401</enddate><creator>Fukuhara, Motomitsu</creator><creator>Urabe, Yuji</creator><creator>Nakamura, Takeo</creator><creator>Ishibashi, Kazuki</creator><creator>Konishi, Hirona</creator><creator>Mizuno, Junichi</creator><creator>Takasago, Takeshi</creator><creator>Tanaka, Hidenori</creator><creator>Tsuboi, Akiyoshi</creator><creator>Yamashita, Ken</creator><creator>Hiyama, Yuichi</creator><creator>Takigawa, Hidehiko</creator><creator>Kotachi, Takahiro</creator><creator>Yuge, Ryo</creator><creator>Ishikawa, Akira</creator><creator>Taruya, Takayuki</creator><creator>Ueda, Tsutomu</creator><creator>Takeno, Sachio</creator><creator>Oka, Shiro</creator><general>John Wiley and Sons Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-4154-658X</orcidid><orcidid>https://orcid.org/0000-0002-1652-0743</orcidid><orcidid>https://orcid.org/0009-0009-9851-8564</orcidid><orcidid>https://orcid.org/0000-0002-1528-1939</orcidid><orcidid>https://orcid.org/0000-0002-3646-5796</orcidid></search><sort><creationdate>20250401</creationdate><title>Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas</title><author>Fukuhara, Motomitsu ; Urabe, Yuji ; Nakamura, Takeo ; Ishibashi, Kazuki ; Konishi, Hirona ; Mizuno, Junichi ; Takasago, Takeshi ; Tanaka, Hidenori ; Tsuboi, Akiyoshi ; Yamashita, Ken ; Hiyama, Yuichi ; Takigawa, Hidehiko ; Kotachi, Takahiro ; Yuge, Ryo ; Ishikawa, Akira ; Taruya, Takayuki ; Ueda, Tsutomu ; Takeno, Sachio ; Oka, Shiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c268t-e67af039999957948ac54f72aa5fc5acf73ad2447236c5fc38e00cf902588883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><topic>Original</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fukuhara, Motomitsu</creatorcontrib><creatorcontrib>Urabe, Yuji</creatorcontrib><creatorcontrib>Nakamura, Takeo</creatorcontrib><creatorcontrib>Ishibashi, Kazuki</creatorcontrib><creatorcontrib>Konishi, Hirona</creatorcontrib><creatorcontrib>Mizuno, Junichi</creatorcontrib><creatorcontrib>Takasago, Takeshi</creatorcontrib><creatorcontrib>Tanaka, Hidenori</creatorcontrib><creatorcontrib>Tsuboi, Akiyoshi</creatorcontrib><creatorcontrib>Yamashita, Ken</creatorcontrib><creatorcontrib>Hiyama, Yuichi</creatorcontrib><creatorcontrib>Takigawa, Hidehiko</creatorcontrib><creatorcontrib>Kotachi, Takahiro</creatorcontrib><creatorcontrib>Yuge, Ryo</creatorcontrib><creatorcontrib>Ishikawa, Akira</creatorcontrib><creatorcontrib>Taruya, Takayuki</creatorcontrib><creatorcontrib>Ueda, Tsutomu</creatorcontrib><creatorcontrib>Takeno, Sachio</creatorcontrib><creatorcontrib>Oka, Shiro</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>DEN open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fukuhara, Motomitsu</au><au>Urabe, Yuji</au><au>Nakamura, Takeo</au><au>Ishibashi, Kazuki</au><au>Konishi, Hirona</au><au>Mizuno, Junichi</au><au>Takasago, Takeshi</au><au>Tanaka, Hidenori</au><au>Tsuboi, Akiyoshi</au><au>Yamashita, Ken</au><au>Hiyama, Yuichi</au><au>Takigawa, Hidehiko</au><au>Kotachi, Takahiro</au><au>Yuge, Ryo</au><au>Ishikawa, Akira</au><au>Taruya, Takayuki</au><au>Ueda, Tsutomu</au><au>Takeno, Sachio</au><au>Oka, Shiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas</atitle><jtitle>DEN open</jtitle><addtitle>DEN Open</addtitle><date>2025-04-01</date><risdate>2025</risdate><volume>5</volume><issue>1</issue><spage>e70003</spage><pages>e70003-</pages><issn>2692-4609</issn><eissn>2692-4609</eissn><abstract>Endoscopic treatment of superficial pharyngeal carcinomas includes endoscopic submucosal dissection (ESD; usually performed by endoscopists), and endoscopic laryngo-pharyngeal surgery (ELPS; primarily performed by otolaryngologists). Few studies have compared the efficacy of the two techniques in treating superficial pharyngeal carcinomas. In this study, we compared the outcomes of these two techniques to determine the advantages.
We retrospectively examined the short- and long-term outcomes of 93 consecutive patients with superficial pharyngeal carcinoma who either underwent an ESD or ELPS between August 2008 and December 2021.
There were 35 lesions among 29 patients and 93 lesions among 71 patients in the ESD and ELPS groups, respectively. The ELPS group had a significantly shorter procedure time (121.2 ± 97.4 min vs. 54.7 ± 40.2 min, p<0.01), greater procedure speed (0.10 ± 0.06 min/min vs. 0.30 ± 0.23 min/min, p<0.01), and less laryngeal edema than that of the ESD group. There were no significant differences in the 3-year overall, relapse-free, or disease-specific survival rates between the two groups. Intervention with ESD during ELPS was most commonly required when it was difficult to secure the visual field.
There were no differences in batch resection rates or long-term prognoses between the two groups; nevertheless, the ELPS group had a shorter treatment time and less laryngeal edema than the ESD group. However, the treatment of narrow areas, such as the esophageal inlet patch, is a technical limitation of ELPS; thus, ELPS should be combined with ESD techniques.</abstract><cop>Australia</cop><pub>John Wiley and Sons Inc</pub><pmid>39268174</pmid><doi>10.1002/deo2.70003</doi><orcidid>https://orcid.org/0000-0003-4154-658X</orcidid><orcidid>https://orcid.org/0000-0002-1652-0743</orcidid><orcidid>https://orcid.org/0009-0009-9851-8564</orcidid><orcidid>https://orcid.org/0000-0002-1528-1939</orcidid><orcidid>https://orcid.org/0000-0002-3646-5796</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2692-4609 |
| ispartof | DEN open, 2025-04, Vol.5 (1), p.e70003 |
| issn | 2692-4609 2692-4609 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11391100 |
| source | Wiley Online Library Open Access; DOAJ Directory of Open Access Journals; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Original |
| title | Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T08%3A25%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparative%20analyses%20of%20short-%20and%20long-term%20outcomes%20between%20endoscopic%20submucosal%20dissection%20and%20endoscopic%20laryngo-pharyngeal%20surgery%20for%20superficial%20pharyngeal%20carcinomas&rft.jtitle=DEN%20open&rft.au=Fukuhara,%20Motomitsu&rft.date=2025-04-01&rft.volume=5&rft.issue=1&rft.spage=e70003&rft.pages=e70003-&rft.issn=2692-4609&rft.eissn=2692-4609&rft_id=info:doi/10.1002/deo2.70003&rft_dat=%3Cproquest_pubme%3E3104528214%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3104528214&rft_id=info:pmid/39268174&rfr_iscdi=true |