Complete or Culprit-Only PCI in Older Patients with MI
To the Editor: In their article on the FIRE trial, Biscaglia et al. (Sept. 7 issue) 1 state that the use of physiology-guided complete revascularization resulted in a lower risk of death from cardiovascular or other causes than percutaneous coronary intervention (PCI) alone in older patients (age, ≥...
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| Veröffentlicht in: | The New England journal of medicine 2023-11, Vol.389 (20), p.1922-1924 |
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| container_issue | 20 |
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| container_title | The New England journal of medicine |
| container_volume | 389 |
| creator | Durai, Vivek Mallidi, Jaya Madsen, Jasmine M. Engstrøm, Thomas Sanchis, Juan Ariza-Solé, Albert Alfonso, Fernando Mone, Pasquale Guerra, Germano Santulli, Gaetano Biscaglia, Simone Campo, Gianluca |
| description | To the Editor:
In their article on the FIRE trial, Biscaglia et al. (Sept. 7 issue)
1
state that the use of physiology-guided complete revascularization resulted in a lower risk of death from cardiovascular or other causes than percutaneous coronary intervention (PCI) alone in older patients (age, ≥75 years) with myocardial infarction and multivessel disease. This reduction in overall mortality was unexpected because such a benefit has not been reported in previous randomized, controlled trials comparing invasive strategies with conservative strategies among older patients with non–ST-segment elevation myocardial infarction (NSTEMI) or comparing complete versus culprit-only revascularization among patients with ST-segment elevation . . . |
| doi_str_mv | 10.1056/NEJMc2311551 |
| format | Article |
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In their article on the FIRE trial, Biscaglia et al. (Sept. 7 issue)
1
state that the use of physiology-guided complete revascularization resulted in a lower risk of death from cardiovascular or other causes than percutaneous coronary intervention (PCI) alone in older patients (age, ≥75 years) with myocardial infarction and multivessel disease. This reduction in overall mortality was unexpected because such a benefit has not been reported in previous randomized, controlled trials comparing invasive strategies with conservative strategies among older patients with non–ST-segment elevation myocardial infarction (NSTEMI) or comparing complete versus culprit-only revascularization among patients with ST-segment elevation . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>ISSN: 1533-4406</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc2311551</identifier><identifier>PMID: 37966296</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Aged ; Cardiovascular diseases ; Clinical trials ; Conflicts of interest ; Coronary Artery Disease ; Frailty ; Humans ; Medical imaging ; Mortality ; Myocardial infarction ; Myocardial Infarction - therapy ; Percutaneous Coronary Intervention</subject><ispartof>The New England journal of medicine, 2023-11, Vol.389 (20), p.1922-1924</ispartof><rights>Copyright © 2023 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5961-454dd119836c473a0fdad4317d16de363183e1550a10c7314dfc4e246a7b291c3</citedby><cites>FETCH-LOGICAL-c5961-454dd119836c473a0fdad4317d16de363183e1550a10c7314dfc4e246a7b291c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc2311551$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2890406283?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,780,784,885,2759,2760,26103,27924,27925,52382,54064,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37966296$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Durai, Vivek</creatorcontrib><creatorcontrib>Mallidi, Jaya</creatorcontrib><creatorcontrib>Madsen, Jasmine M.</creatorcontrib><creatorcontrib>Engstrøm, Thomas</creatorcontrib><creatorcontrib>Sanchis, Juan</creatorcontrib><creatorcontrib>Ariza-Solé, Albert</creatorcontrib><creatorcontrib>Alfonso, Fernando</creatorcontrib><creatorcontrib>Mone, Pasquale</creatorcontrib><creatorcontrib>Guerra, Germano</creatorcontrib><creatorcontrib>Santulli, Gaetano</creatorcontrib><creatorcontrib>Biscaglia, Simone</creatorcontrib><creatorcontrib>Campo, Gianluca</creatorcontrib><title>Complete or Culprit-Only PCI in Older Patients with MI</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
In their article on the FIRE trial, Biscaglia et al. (Sept. 7 issue)
1
state that the use of physiology-guided complete revascularization resulted in a lower risk of death from cardiovascular or other causes than percutaneous coronary intervention (PCI) alone in older patients (age, ≥75 years) with myocardial infarction and multivessel disease. This reduction in overall mortality was unexpected because such a benefit has not been reported in previous randomized, controlled trials comparing invasive strategies with conservative strategies among older patients with non–ST-segment elevation myocardial infarction (NSTEMI) or comparing complete versus culprit-only revascularization among patients with ST-segment elevation . . .</description><subject>Aged</subject><subject>Cardiovascular diseases</subject><subject>Clinical trials</subject><subject>Conflicts of interest</subject><subject>Coronary Artery Disease</subject><subject>Frailty</subject><subject>Humans</subject><subject>Medical imaging</subject><subject>Mortality</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - therapy</subject><subject>Percutaneous Coronary Intervention</subject><issn>0028-4793</issn><issn>1533-4406</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0r1PAyEYBnBiNFqrm7O5RAcHT3mB447JmEvVGrUOOhMKVK-5jwp3mv73olVTjUNZGPjlyZuHF6E9wCeAE356N7i-1YQCJAmsoR4klMaMYb6OehiTLGapoFto2_spDgeY2ERbNBWcE8F7iOdNNStta6PGRXlXzlzRxqO6nEf3-TAq6mhUGuuie9UWtm599Fa0z9HtcAdtTFTp7e7X3UePF4OH_Cq-GV0O8_ObWCeCQ8wSZgyAyCjXLKUKT4wyjEJqgBtLOYWM2jA4VoB1SoGZiWaWMK7SMRGgaR-dLXJn3biyRocZnCplmLJSbi4bVcjfL3XxLJ-aVwlAswxSEhKOvhJc89JZ38qq8NqWpapt03lJMoEpD-2lq1O-IsWCsJUpiEAP_tBp07k6FPypwqeSjAZ1vFDaNd47O_mpA7D8WAm5vBKB7y9X-IO_dyCAwwWoKi9rO63-z3kHNRi3aQ</recordid><startdate>20231116</startdate><enddate>20231116</enddate><creator>Durai, Vivek</creator><creator>Mallidi, Jaya</creator><creator>Madsen, Jasmine M.</creator><creator>Engstrøm, Thomas</creator><creator>Sanchis, Juan</creator><creator>Ariza-Solé, Albert</creator><creator>Alfonso, Fernando</creator><creator>Mone, Pasquale</creator><creator>Guerra, Germano</creator><creator>Santulli, Gaetano</creator><creator>Biscaglia, Simone</creator><creator>Campo, Gianluca</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20231116</creationdate><title>Complete or Culprit-Only PCI in Older Patients with MI</title><author>Durai, Vivek ; Mallidi, Jaya ; Madsen, Jasmine M. ; Engstrøm, Thomas ; Sanchis, Juan ; Ariza-Solé, Albert ; Alfonso, Fernando ; Mone, Pasquale ; Guerra, Germano ; Santulli, Gaetano ; Biscaglia, Simone ; Campo, Gianluca</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5961-454dd119836c473a0fdad4317d16de363183e1550a10c7314dfc4e246a7b291c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Aged</topic><topic>Cardiovascular diseases</topic><topic>Clinical trials</topic><topic>Conflicts of interest</topic><topic>Coronary Artery Disease</topic><topic>Frailty</topic><topic>Humans</topic><topic>Medical imaging</topic><topic>Mortality</topic><topic>Myocardial infarction</topic><topic>Myocardial Infarction - therapy</topic><topic>Percutaneous Coronary Intervention</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Durai, Vivek</creatorcontrib><creatorcontrib>Mallidi, Jaya</creatorcontrib><creatorcontrib>Madsen, Jasmine M.</creatorcontrib><creatorcontrib>Engstrøm, Thomas</creatorcontrib><creatorcontrib>Sanchis, Juan</creatorcontrib><creatorcontrib>Ariza-Solé, Albert</creatorcontrib><creatorcontrib>Alfonso, Fernando</creatorcontrib><creatorcontrib>Mone, Pasquale</creatorcontrib><creatorcontrib>Guerra, Germano</creatorcontrib><creatorcontrib>Santulli, Gaetano</creatorcontrib><creatorcontrib>Biscaglia, Simone</creatorcontrib><creatorcontrib>Campo, Gianluca</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Durai, Vivek</au><au>Mallidi, Jaya</au><au>Madsen, Jasmine M.</au><au>Engstrøm, Thomas</au><au>Sanchis, Juan</au><au>Ariza-Solé, Albert</au><au>Alfonso, Fernando</au><au>Mone, Pasquale</au><au>Guerra, Germano</au><au>Santulli, Gaetano</au><au>Biscaglia, Simone</au><au>Campo, Gianluca</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Complete or Culprit-Only PCI in Older Patients with MI</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2023-11-16</date><risdate>2023</risdate><volume>389</volume><issue>20</issue><spage>1922</spage><epage>1924</epage><pages>1922-1924</pages><issn>0028-4793</issn><issn>1533-4406</issn><eissn>1533-4406</eissn><abstract>To the Editor:
In their article on the FIRE trial, Biscaglia et al. (Sept. 7 issue)
1
state that the use of physiology-guided complete revascularization resulted in a lower risk of death from cardiovascular or other causes than percutaneous coronary intervention (PCI) alone in older patients (age, ≥75 years) with myocardial infarction and multivessel disease. This reduction in overall mortality was unexpected because such a benefit has not been reported in previous randomized, controlled trials comparing invasive strategies with conservative strategies among older patients with non–ST-segment elevation myocardial infarction (NSTEMI) or comparing complete versus culprit-only revascularization among patients with ST-segment elevation . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>37966296</pmid><doi>10.1056/NEJMc2311551</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2023-11, Vol.389 (20), p.1922-1924 |
| issn | 0028-4793 1533-4406 1533-4406 |
| language | eng |
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| source | MEDLINE; New England Journal of Medicine Current; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland |
| subjects | Aged Cardiovascular diseases Clinical trials Conflicts of interest Coronary Artery Disease Frailty Humans Medical imaging Mortality Myocardial infarction Myocardial Infarction - therapy Percutaneous Coronary Intervention |
| title | Complete or Culprit-Only PCI in Older Patients with MI |
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