Brain organoids: A new tool for modelling of neurodevelopmental disorders

Neurodevelopmental disorders are mostly studied using mice as models. However, the mouse brain lacks similar cell types and structures as those of the human brain. In recent years, emergence of three‐dimensional brain organoids derived from human embryonic stem cells or induced pluripotent stem cell...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2024-09, Vol.28 (17), p.e18560-n/a
Hauptverfasser:	Aili, Yirizhati, Maimaitiming, Nuersimanguli, Wang, Zengliang, Wang, Yongxin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Brain - cytology Brain - growth & development Brain - pathology brain organoids Brain research Cell culture Developmental stages Disease Embryo cells Embryogenesis Genes Humans Hypothalamus induced pluripotent stem cells Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Maturation Models, Biological Nervous system Neural networks Neural stem cells Neurobiology neurodevelopmental diseases Neurodevelopmental disorders Neurodevelopmental Disorders - pathology Neurosciences Organoids Pathogenesis Pluripotency preclinical models Review Stem cells
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