Correlation between systemic allergen desensitisation and long-term asthma protection in mice following intravenous administration of the live tuberculosis vaccine MTBVAC

MTBVAC is a live attenuated tuberculosis vaccine, currently undergoing phase III evaluation for tuberculosis prevention. In previous preclinical studies, we found that local pulmonary administration of MTBVAC via the intranasal route had a strong therapeutic effect against asthma. This effect correl...

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Veröffentlicht in:	EBioMedicine 2024-09, Vol.107, p.105272, Article 105272
Hauptverfasser:	Calvo, Silvia, Rodrigo-Muñoz, Jose Manuel, Tarancón, Raquel, Uranga, Santiago, Martín, Carlos, Pozo, Victoria del, Aguiló, Nacho
Format:	Artikel
Sprache:	eng
Schlagworte:	Asthma Eosinophilia Intravenous inoculation Live tuberculosis vaccines MTBVAC Th2/Th1 lymphocytes
Online-Zugang:	Volltext
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