Pharmacokinetic interaction between regorafenib and atorvastatin in rats

Background Regorafenib is used in the treatment of colorectal cancer and hepatocellular carcinoma. Due to the co-morbidity of hyperlipidemia in these conditions, statins, including atorvastatin, are used as potential adjuvant therapy agents. Both regorafenib and atorvastatin are metabolized by CYP3A...

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Veröffentlicht in:	Pharmacological reports 2024-10, Vol.76 (5), p.1184-1195
Hauptverfasser:	Szkutnik-Fiedler, Danuta, Szałek, Edyta, Otto, Filip, Czyrski, Andrzej, Karaźniewicz-Łada, Marta, Wolc, Anna, Grześkowiak, Edmund, Lewandowski, Konrad, Karbownik, Agnieszka
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Safety and Pharmacovigilance Medicine Pharmacotherapy Pharmacy Short Communication
Online-Zugang:	Volltext
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