Methionine as a regulator of bone remodeling with fasting

Caloric restriction improves metabolic health but is often complicated by bone loss. We studied bone parameters in humans during a 10-day fast and identified candidate metabolic regulators of bone turnover. Pro-collagen 1 intact N-terminal pro-peptide (P1NP), a bone formation marker, decreased withi...

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Veröffentlicht in:	JCI insight 2024-05, Vol.9 (12)
Hauptverfasser:	Amorim, Tânia, Kumar, Naveen Gv, David, Natalie L, Dion, William, Pagadala, Trishya, Doshi, Nandini K, Zhu, Bokai, Parkhitko, Andrey, Steinhauser, Matthew L, Fazeli, Pouneh K
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Adult Animals Bone Density - drug effects Bone Remodeling - drug effects Bone Remodeling - physiology Caloric Restriction Fasting Female Humans Male Methionine - administration & dosage Methionine - metabolism Mice Middle Aged Osteoblasts - metabolism Peptide Fragments - blood Peptide Fragments - metabolism Procollagen - blood Procollagen - metabolism
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