Mortality risk factors for crush syndrome after an earthquake in Türkiye: Do systemic inflammatory parameters play any role?
The aim of our study is to assess the prognostic impact of the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) on 28-day mortality in patients admitted to the intensive care unit with crush syndrome following the Kahramanmaraş earthqua...
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| Veröffentlicht in: | Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 2024-08, Vol.30 (8), p.588-595 |
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| container_title | Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES |
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| creator | Türktan, Mediha Doğan, Ömer Gök, Mehmet Gökhan Aydın, Kaniye Güleç, Ersel Hatipoğlu, Zehra Arslan, Yusuf Kemal Özcengiz, Dilek |
| description | The aim of our study is to assess the prognostic impact of the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) on 28-day mortality in patients admitted to the intensive care unit with crush syndrome following the Kahramanmaraş earthquake in Türkiye.
A total of 63 adult patients with crush syndrome admitted to the intensive care unit after the earthquake were enrolled in this study. The medical records of the patients were examined using follow-up forms and the hospital data system.
The mean age of the patients was 38.9±17.3 years, and the median time under debris was 31.5 hours. The 28-day mortality rate was 27%. In univariate generalized estimating equations (GEE) and other analyses, variables that are significant (or candidate variables) between 28-day mortality groups included age as a biological factor. These variables were included in the multivariate GEE model. The effects of continuous renal replacement therapy (CRRT), serum sodium concentration, Sequential Organ Failure Assessment (SOFA) score, and PLR on mortality were statistically significant.
Elevated SOFA scores, the necessity for CRRT, increased serum sodium levels, and decreased PLR values are associated with increased 28-day mortality in patients with crush syndrome after an earthquake. |
| doi_str_mv | 10.14744/tjtes.2024.09637 |
| format | Article |
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A total of 63 adult patients with crush syndrome admitted to the intensive care unit after the earthquake were enrolled in this study. The medical records of the patients were examined using follow-up forms and the hospital data system.
The mean age of the patients was 38.9±17.3 years, and the median time under debris was 31.5 hours. The 28-day mortality rate was 27%. In univariate generalized estimating equations (GEE) and other analyses, variables that are significant (or candidate variables) between 28-day mortality groups included age as a biological factor. These variables were included in the multivariate GEE model. The effects of continuous renal replacement therapy (CRRT), serum sodium concentration, Sequential Organ Failure Assessment (SOFA) score, and PLR on mortality were statistically significant.
Elevated SOFA scores, the necessity for CRRT, increased serum sodium levels, and decreased PLR values are associated with increased 28-day mortality in patients with crush syndrome after an earthquake.</description><identifier>ISSN: 1306-696X</identifier><identifier>EISSN: 1307-7945</identifier><identifier>DOI: 10.14744/tjtes.2024.09637</identifier><identifier>PMID: 39092965</identifier><language>eng</language><publisher>Turkey: KARE Publishing</publisher><subject>Adult ; Aged ; Crush Syndrome - blood ; Crush Syndrome - complications ; Crush Syndrome - mortality ; Earthquakes ; Female ; Health aspects ; Hospital patients ; Humans ; Lymphocytes ; Male ; Medical records ; Medical research ; Medicine, Experimental ; Middle Aged ; Mortality ; Original ; Prognosis ; Risk Factors ; Turkey - epidemiology ; Young Adult</subject><ispartof>Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2024-08, Vol.30 (8), p.588-595</ispartof><rights>COPYRIGHT 2024 KARE Publishing</rights><rights>Copyright © 2024 Turkish Journal of Trauma and Emergency Surgery 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372493/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372493/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39092965$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Türktan, Mediha</creatorcontrib><creatorcontrib>Doğan, Ömer</creatorcontrib><creatorcontrib>Gök, Mehmet Gökhan</creatorcontrib><creatorcontrib>Aydın, Kaniye</creatorcontrib><creatorcontrib>Güleç, Ersel</creatorcontrib><creatorcontrib>Hatipoğlu, Zehra</creatorcontrib><creatorcontrib>Arslan, Yusuf Kemal</creatorcontrib><creatorcontrib>Özcengiz, Dilek</creatorcontrib><title>Mortality risk factors for crush syndrome after an earthquake in Türkiye: Do systemic inflammatory parameters play any role?</title><title>Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES</title><addtitle>Ulus Travma Acil Cerrahi Derg</addtitle><description>The aim of our study is to assess the prognostic impact of the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) on 28-day mortality in patients admitted to the intensive care unit with crush syndrome following the Kahramanmaraş earthquake in Türkiye.
A total of 63 adult patients with crush syndrome admitted to the intensive care unit after the earthquake were enrolled in this study. The medical records of the patients were examined using follow-up forms and the hospital data system.
The mean age of the patients was 38.9±17.3 years, and the median time under debris was 31.5 hours. The 28-day mortality rate was 27%. In univariate generalized estimating equations (GEE) and other analyses, variables that are significant (or candidate variables) between 28-day mortality groups included age as a biological factor. These variables were included in the multivariate GEE model. The effects of continuous renal replacement therapy (CRRT), serum sodium concentration, Sequential Organ Failure Assessment (SOFA) score, and PLR on mortality were statistically significant.
Elevated SOFA scores, the necessity for CRRT, increased serum sodium levels, and decreased PLR values are associated with increased 28-day mortality in patients with crush syndrome after an earthquake.</description><subject>Adult</subject><subject>Aged</subject><subject>Crush Syndrome - blood</subject><subject>Crush Syndrome - complications</subject><subject>Crush Syndrome - mortality</subject><subject>Earthquakes</subject><subject>Female</subject><subject>Health aspects</subject><subject>Hospital patients</subject><subject>Humans</subject><subject>Lymphocytes</subject><subject>Male</subject><subject>Medical records</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Original</subject><subject>Prognosis</subject><subject>Risk Factors</subject><subject>Turkey - epidemiology</subject><subject>Young Adult</subject><issn>1306-696X</issn><issn>1307-7945</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptUctu1DAUtRCIVqUfwAZZYp3Br9gxm6oqT6mITZHYWTeO3XEniQfbg5QFf8aOH8MzAxWVkBe27nlc33sQek7JigolxKtyV1xeMcLEimjJ1SN0SjlRjdKifXx4y0Zq-fUEned8RwihlGtO1VN0wjXRTMv2FP34FFOBMZQFp5A32IMtMWXsY8I27fIa52UeUpwcBl9cwjBjB6msv-1g43CY8c2vn2kTFvcav4mVnIubgq2AH2GaoJoteAsJJlfVGW9HWKpH7RZHd_EMPfEwZnf-5z5DX969vbn60Fx_fv_x6vK6sVzo0nDf0baDjnolvLa97ilvKVUDl4T3VnjfMwYtYR2XvMIMHB2s7Sl4byXR_AxdHH23u35yg3VzSTCabQoTpMVECOYhMoe1uY3fTV2ZYkLz6vDy6HALozN1ulh5dgrZmsuOqFYq1u37rP7DqmfYLyXOzodafyCgR4FNMefk_P2fKDGHmM0hZrOP2RxirpoX_w5zr_gbKv8NiYKoSQ</recordid><startdate>20240801</startdate><enddate>20240801</enddate><creator>Türktan, Mediha</creator><creator>Doğan, Ömer</creator><creator>Gök, Mehmet Gökhan</creator><creator>Aydın, Kaniye</creator><creator>Güleç, Ersel</creator><creator>Hatipoğlu, Zehra</creator><creator>Arslan, Yusuf Kemal</creator><creator>Özcengiz, Dilek</creator><general>KARE Publishing</general><general>Kare Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20240801</creationdate><title>Mortality risk factors for crush syndrome after an earthquake in Türkiye: Do systemic inflammatory parameters play any role?</title><author>Türktan, Mediha ; Doğan, Ömer ; Gök, Mehmet Gökhan ; Aydın, Kaniye ; Güleç, Ersel ; Hatipoğlu, Zehra ; Arslan, Yusuf Kemal ; Özcengiz, Dilek</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-3f8158a81f74f9cb9b135117d3603bc4ffb22a5028363cb92ae1dccb1affc6093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Crush Syndrome - blood</topic><topic>Crush Syndrome - complications</topic><topic>Crush Syndrome - mortality</topic><topic>Earthquakes</topic><topic>Female</topic><topic>Health aspects</topic><topic>Hospital patients</topic><topic>Humans</topic><topic>Lymphocytes</topic><topic>Male</topic><topic>Medical records</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Original</topic><topic>Prognosis</topic><topic>Risk Factors</topic><topic>Turkey - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Türktan, Mediha</creatorcontrib><creatorcontrib>Doğan, Ömer</creatorcontrib><creatorcontrib>Gök, Mehmet Gökhan</creatorcontrib><creatorcontrib>Aydın, Kaniye</creatorcontrib><creatorcontrib>Güleç, Ersel</creatorcontrib><creatorcontrib>Hatipoğlu, Zehra</creatorcontrib><creatorcontrib>Arslan, Yusuf Kemal</creatorcontrib><creatorcontrib>Özcengiz, Dilek</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Türktan, Mediha</au><au>Doğan, Ömer</au><au>Gök, Mehmet Gökhan</au><au>Aydın, Kaniye</au><au>Güleç, Ersel</au><au>Hatipoğlu, Zehra</au><au>Arslan, Yusuf Kemal</au><au>Özcengiz, Dilek</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mortality risk factors for crush syndrome after an earthquake in Türkiye: Do systemic inflammatory parameters play any role?</atitle><jtitle>Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES</jtitle><addtitle>Ulus Travma Acil Cerrahi Derg</addtitle><date>2024-08-01</date><risdate>2024</risdate><volume>30</volume><issue>8</issue><spage>588</spage><epage>595</epage><pages>588-595</pages><issn>1306-696X</issn><eissn>1307-7945</eissn><abstract>The aim of our study is to assess the prognostic impact of the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) on 28-day mortality in patients admitted to the intensive care unit with crush syndrome following the Kahramanmaraş earthquake in Türkiye.
A total of 63 adult patients with crush syndrome admitted to the intensive care unit after the earthquake were enrolled in this study. The medical records of the patients were examined using follow-up forms and the hospital data system.
The mean age of the patients was 38.9±17.3 years, and the median time under debris was 31.5 hours. The 28-day mortality rate was 27%. In univariate generalized estimating equations (GEE) and other analyses, variables that are significant (or candidate variables) between 28-day mortality groups included age as a biological factor. These variables were included in the multivariate GEE model. The effects of continuous renal replacement therapy (CRRT), serum sodium concentration, Sequential Organ Failure Assessment (SOFA) score, and PLR on mortality were statistically significant.
Elevated SOFA scores, the necessity for CRRT, increased serum sodium levels, and decreased PLR values are associated with increased 28-day mortality in patients with crush syndrome after an earthquake.</abstract><cop>Turkey</cop><pub>KARE Publishing</pub><pmid>39092965</pmid><doi>10.14744/tjtes.2024.09637</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2024-08, Vol.30 (8), p.588-595 |
| issn | 1306-696X 1307-7945 |
| language | eng |
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| source | MEDLINE; PubMed Central Open Access; PubMed Central |
| subjects | Adult Aged Crush Syndrome - blood Crush Syndrome - complications Crush Syndrome - mortality Earthquakes Female Health aspects Hospital patients Humans Lymphocytes Male Medical records Medical research Medicine, Experimental Middle Aged Mortality Original Prognosis Risk Factors Turkey - epidemiology Young Adult |
| title | Mortality risk factors for crush syndrome after an earthquake in Türkiye: Do systemic inflammatory parameters play any role? |
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