Differential Responses to Aging Among the Transcriptome and Proteome of Mesenchymal Progenitor Populations

Abstract The biological aging of stem cells (exhaustion) is proposed to contribute to the development of a variety of age-related conditions. Despite this, little is understood about the specific mechanisms which drive this process. In this study, we assess the transcriptomic and proteomic changes i...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2024-09, Vol.79 (9)
Hauptverfasser:	Feehan, Jack, Tripodi, Nicholas, Kondrikov, Dmitry, Wijeratne, Tissa, Gimble, Jeffrey, Hill, William, Apostolopoulos, Vasso, Duque, Gustavo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aging - genetics Aging - physiology Cell Differentiation Cell Proliferation - genetics Cellular Senescence - genetics Cellular Senescence - physiology Female Humans Male Mesenchymal Stem Cells - metabolism Middle Aged Proteome Proteomics THE JOURNAL OF GERONTOLOGY: Biological Sciences Transcriptome Young Adult
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