Mutation-deletion analysis of a Ca(2+)-dependent phospholipid binding (CaLB) domain within p120 GAP, a GTPase-activating protein for p21 ras

p120 GAP is a GTPase activating protein for p21 ras. It is a multidomain protein which exhibits sequence similarity with other GTPase-activating proteins, src, pleckstrin and a central portion of the protein kinase C conserved region 2 domain known as CaLB (Ca(2+)-dependent phospholipid-binding). Th...

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Veröffentlicht in:	Biochemical journal 1995-04, Vol.307 ( Pt 2) (Pt 2), p.487-491
Hauptverfasser:	Gawler, D J, Zhang, L J, Moran, M F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Binding Sites Calcium - metabolism DNA Mutational Analysis GTPase-Activating Proteins Humans Molecular Sequence Data Mutation Oncogene Protein p21(ras) - metabolism Phospholipids - metabolism Proteins - genetics Proteins - metabolism ras GTPase-Activating Proteins Recombinant Fusion Proteins - metabolism Sequence Deletion
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