Idiopathic dendriform pulmonary ossification as the phenotype of interstitial lung abnormalities: CT–pathologic correlation and prevalence
Background and purpose Idiopathic dendriform pulmonary ossification (DPO) is mostly asymptomatic, and detected incidentally in lung CT. There have been no reports on the precise CT–pathologic correlation and the prevalence of idiopathic DPO. This study aimed to clarify the histological background an...
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| Veröffentlicht in: | Japanese journal of radiology 2024-09, Vol.42 (9), p.993-1002 |
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| creator | Ueno, Midori Egashira, Ryoko Hashisako, Mikiko Fujimoto, Kiminori Fukuda, Taiki Hayashida, Yoshiko Sumikawa, Hiromitsu Tominaga, Junya Tanaka, Tomonori Terasaki, Yasuhiro Fukuoka, Junya Nishioka, Yasuhiko Aoki, Takatoshi Gabata, Toshifumi Hatabu, Hiroto Johkoh, Takeshi |
| description | Background and purpose
Idiopathic dendriform pulmonary ossification (DPO) is mostly asymptomatic, and detected incidentally in lung CT. There have been no reports on the precise CT–pathologic correlation and the prevalence of idiopathic DPO. This study aimed to clarify the histological background and prevalence of idiopathic DPO.
Materials and methods
Sixteen patients with histologically confirmed idiopathic DPO (12 men and 4 women; mean age, 38.8 years; range 22–56 years) were identified in a nationwide epidemiological survey. Local HRCT findings of pre-biopsy examinations, such as branching, round, linear structures with or without high attenuation were compared side by side with histological findings. The attenuation of branching, round, and linear structures was classified into three-point levels on bone window images (width, 2500 HU; level, 500 HU). Furthermore, we collected continuous pulmonary CT images of 8111 cases for checking up metastasis from extrathoracic malignancy at a single institution, and evaluated the prevalence of interstitial lung abnormalities (ILAs) and DPO.
Results
In all 16 cases, branching (
n
= 15, 93%), round (
n
= 5, 31%), or linear (
n
= 5, 31%) structures were identified, histologically corresponding to dendriform ossification and cicatricial organizing pneumonia (OP)/fibrosis. Histologically, ossification was confirmed in all the 16 patients. However, in two cases, a highly attenuated structure could not be detected on the pre-biopsy CT of the same area. Regarding the prevalence of idiopathic DPO, 283 (3.5%) of 8111 patients had ILAs, of which a total of 26 (0.3% of all cases, 9.2% of ILAs cases) had DPO.
Conclusion
Idiopathic DPO showed linear or branching structures with or without high attenuation on CT, corresponded to ossification, cicatricial OP/fibrosis. DPO was seen in 9.2% of ILAs cases. Idiopathic DPO is one of pathologic phenotypes of ILAs. |
| doi_str_mv | 10.1007/s11604-024-01590-8 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11364601</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3054840361</sourcerecordid><originalsourceid>FETCH-LOGICAL-c492t-e8431771d26e46d5cf1880e87ee469a1cc04e4e3b4013a03104b0d9298849c2c3</originalsourceid><addsrcrecordid>eNp9kc2OFCEQx4nRuOvoC3gwJF68tFIN3U17MWbixyabeFkTb4Shq2fY0NACvcnefABvvqFPIuOM48fBA4GifvUvij8hj4E9B8a6FwmgZaJidVnQ9KySd8g5yLargMlPd0_nDs7Ig5SuGWsFF-I-OeOyEyWoz8nXi8GGWeedNXRAP0Q7hjjReXFT8Dre0pCSHa3R2QZPdaJ5h3TeoQ_5dkYaRmp9xpiyzVY76ha_pXrji4Z25QrTS7q--v7l275FcGFb2pgQI7qjoB_oHPFGO_QGH5J7o3YJHx33Ffn49s3V-n11-eHdxfr1ZWVEX-cKpeDQdTDULYp2aMwIUjKUHZaw12AMEyiQbwQDrhkHJjZs6OteStGb2vAVeXXQnZfNhINBn6N2ao52KiOroK36O-PtTm3DjQLgrWiL6oo8OyrE8HnBlNVkk0HntMewJMVZI6RgvN2jT_9Br8MSfZmvUL3sGxBNXaj6QJlYfjzieHoNMLV3Wx3cVsVt9dNtJUvRkz_nOJX8srcA_ACkkvJbjL97_0f2BxcvugI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3098951452</pqid></control><display><type>article</type><title>Idiopathic dendriform pulmonary ossification as the phenotype of interstitial lung abnormalities: CT–pathologic correlation and prevalence</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Ueno, Midori ; Egashira, Ryoko ; Hashisako, Mikiko ; Fujimoto, Kiminori ; Fukuda, Taiki ; Hayashida, Yoshiko ; Sumikawa, Hiromitsu ; Tominaga, Junya ; Tanaka, Tomonori ; Terasaki, Yasuhiro ; Fukuoka, Junya ; Nishioka, Yasuhiko ; Aoki, Takatoshi ; Gabata, Toshifumi ; Hatabu, Hiroto ; Johkoh, Takeshi</creator><creatorcontrib>Ueno, Midori ; Egashira, Ryoko ; Hashisako, Mikiko ; Fujimoto, Kiminori ; Fukuda, Taiki ; Hayashida, Yoshiko ; Sumikawa, Hiromitsu ; Tominaga, Junya ; Tanaka, Tomonori ; Terasaki, Yasuhiro ; Fukuoka, Junya ; Nishioka, Yasuhiko ; Aoki, Takatoshi ; Gabata, Toshifumi ; Hatabu, Hiroto ; Johkoh, Takeshi</creatorcontrib><description>Background and purpose
Idiopathic dendriform pulmonary ossification (DPO) is mostly asymptomatic, and detected incidentally in lung CT. There have been no reports on the precise CT–pathologic correlation and the prevalence of idiopathic DPO. This study aimed to clarify the histological background and prevalence of idiopathic DPO.
Materials and methods
Sixteen patients with histologically confirmed idiopathic DPO (12 men and 4 women; mean age, 38.8 years; range 22–56 years) were identified in a nationwide epidemiological survey. Local HRCT findings of pre-biopsy examinations, such as branching, round, linear structures with or without high attenuation were compared side by side with histological findings. The attenuation of branching, round, and linear structures was classified into three-point levels on bone window images (width, 2500 HU; level, 500 HU). Furthermore, we collected continuous pulmonary CT images of 8111 cases for checking up metastasis from extrathoracic malignancy at a single institution, and evaluated the prevalence of interstitial lung abnormalities (ILAs) and DPO.
Results
In all 16 cases, branching (
n
= 15, 93%), round (
n
= 5, 31%), or linear (
n
= 5, 31%) structures were identified, histologically corresponding to dendriform ossification and cicatricial organizing pneumonia (OP)/fibrosis. Histologically, ossification was confirmed in all the 16 patients. However, in two cases, a highly attenuated structure could not be detected on the pre-biopsy CT of the same area. Regarding the prevalence of idiopathic DPO, 283 (3.5%) of 8111 patients had ILAs, of which a total of 26 (0.3% of all cases, 9.2% of ILAs cases) had DPO.
Conclusion
Idiopathic DPO showed linear or branching structures with or without high attenuation on CT, corresponded to ossification, cicatricial OP/fibrosis. DPO was seen in 9.2% of ILAs cases. Idiopathic DPO is one of pathologic phenotypes of ILAs.</description><identifier>ISSN: 1867-1071</identifier><identifier>ISSN: 1867-108X</identifier><identifier>EISSN: 1867-108X</identifier><identifier>DOI: 10.1007/s11604-024-01590-8</identifier><identifier>PMID: 38740642</identifier><language>eng</language><publisher>Singapore: Springer Nature Singapore</publisher><subject>Abnormalities ; Adult ; Attenuation ; Biopsy ; Computed tomography ; Epidemiology ; Female ; Fibrosis ; Humans ; Imaging ; Lung - diagnostic imaging ; Lung - pathology ; Lung Diseases, Interstitial - diagnostic imaging ; Lung Diseases, Interstitial - pathology ; Lungs ; Male ; Malignancy ; Medical imaging ; Medicine ; Medicine & Public Health ; Metastases ; Middle Aged ; Nuclear Medicine ; Original ; Original Article ; Ossification ; Ossification, Heterotopic - diagnostic imaging ; Ossification, Heterotopic - pathology ; Phenotype ; Phenotypes ; Prevalence ; Radiology ; Radiotherapy ; Tomography, X-Ray Computed - methods ; Young Adult</subject><ispartof>Japanese journal of radiology, 2024-09, Vol.42 (9), p.993-1002</ispartof><rights>The Author(s) 2024</rights><rights>2024. The Author(s).</rights><rights>The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c492t-e8431771d26e46d5cf1880e87ee469a1cc04e4e3b4013a03104b0d9298849c2c3</cites><orcidid>0009-0000-1506-1306</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11604-024-01590-8$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11604-024-01590-8$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,315,781,785,886,27926,27927,41490,42559,51321</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38740642$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ueno, Midori</creatorcontrib><creatorcontrib>Egashira, Ryoko</creatorcontrib><creatorcontrib>Hashisako, Mikiko</creatorcontrib><creatorcontrib>Fujimoto, Kiminori</creatorcontrib><creatorcontrib>Fukuda, Taiki</creatorcontrib><creatorcontrib>Hayashida, Yoshiko</creatorcontrib><creatorcontrib>Sumikawa, Hiromitsu</creatorcontrib><creatorcontrib>Tominaga, Junya</creatorcontrib><creatorcontrib>Tanaka, Tomonori</creatorcontrib><creatorcontrib>Terasaki, Yasuhiro</creatorcontrib><creatorcontrib>Fukuoka, Junya</creatorcontrib><creatorcontrib>Nishioka, Yasuhiko</creatorcontrib><creatorcontrib>Aoki, Takatoshi</creatorcontrib><creatorcontrib>Gabata, Toshifumi</creatorcontrib><creatorcontrib>Hatabu, Hiroto</creatorcontrib><creatorcontrib>Johkoh, Takeshi</creatorcontrib><title>Idiopathic dendriform pulmonary ossification as the phenotype of interstitial lung abnormalities: CT–pathologic correlation and prevalence</title><title>Japanese journal of radiology</title><addtitle>Jpn J Radiol</addtitle><addtitle>Jpn J Radiol</addtitle><description>Background and purpose
Idiopathic dendriform pulmonary ossification (DPO) is mostly asymptomatic, and detected incidentally in lung CT. There have been no reports on the precise CT–pathologic correlation and the prevalence of idiopathic DPO. This study aimed to clarify the histological background and prevalence of idiopathic DPO.
Materials and methods
Sixteen patients with histologically confirmed idiopathic DPO (12 men and 4 women; mean age, 38.8 years; range 22–56 years) were identified in a nationwide epidemiological survey. Local HRCT findings of pre-biopsy examinations, such as branching, round, linear structures with or without high attenuation were compared side by side with histological findings. The attenuation of branching, round, and linear structures was classified into three-point levels on bone window images (width, 2500 HU; level, 500 HU). Furthermore, we collected continuous pulmonary CT images of 8111 cases for checking up metastasis from extrathoracic malignancy at a single institution, and evaluated the prevalence of interstitial lung abnormalities (ILAs) and DPO.
Results
In all 16 cases, branching (
n
= 15, 93%), round (
n
= 5, 31%), or linear (
n
= 5, 31%) structures were identified, histologically corresponding to dendriform ossification and cicatricial organizing pneumonia (OP)/fibrosis. Histologically, ossification was confirmed in all the 16 patients. However, in two cases, a highly attenuated structure could not be detected on the pre-biopsy CT of the same area. Regarding the prevalence of idiopathic DPO, 283 (3.5%) of 8111 patients had ILAs, of which a total of 26 (0.3% of all cases, 9.2% of ILAs cases) had DPO.
Conclusion
Idiopathic DPO showed linear or branching structures with or without high attenuation on CT, corresponded to ossification, cicatricial OP/fibrosis. DPO was seen in 9.2% of ILAs cases. Idiopathic DPO is one of pathologic phenotypes of ILAs.</description><subject>Abnormalities</subject><subject>Adult</subject><subject>Attenuation</subject><subject>Biopsy</subject><subject>Computed tomography</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Fibrosis</subject><subject>Humans</subject><subject>Imaging</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - pathology</subject><subject>Lung Diseases, Interstitial - diagnostic imaging</subject><subject>Lung Diseases, Interstitial - pathology</subject><subject>Lungs</subject><subject>Male</subject><subject>Malignancy</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastases</subject><subject>Middle Aged</subject><subject>Nuclear Medicine</subject><subject>Original</subject><subject>Original Article</subject><subject>Ossification</subject><subject>Ossification, Heterotopic - diagnostic imaging</subject><subject>Ossification, Heterotopic - pathology</subject><subject>Phenotype</subject><subject>Phenotypes</subject><subject>Prevalence</subject><subject>Radiology</subject><subject>Radiotherapy</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Young Adult</subject><issn>1867-1071</issn><issn>1867-108X</issn><issn>1867-108X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><recordid>eNp9kc2OFCEQx4nRuOvoC3gwJF68tFIN3U17MWbixyabeFkTb4Shq2fY0NACvcnefABvvqFPIuOM48fBA4GifvUvij8hj4E9B8a6FwmgZaJidVnQ9KySd8g5yLargMlPd0_nDs7Ig5SuGWsFF-I-OeOyEyWoz8nXi8GGWeedNXRAP0Q7hjjReXFT8Dre0pCSHa3R2QZPdaJ5h3TeoQ_5dkYaRmp9xpiyzVY76ha_pXrji4Z25QrTS7q--v7l275FcGFb2pgQI7qjoB_oHPFGO_QGH5J7o3YJHx33Ffn49s3V-n11-eHdxfr1ZWVEX-cKpeDQdTDULYp2aMwIUjKUHZaw12AMEyiQbwQDrhkHJjZs6OteStGb2vAVeXXQnZfNhINBn6N2ao52KiOroK36O-PtTm3DjQLgrWiL6oo8OyrE8HnBlNVkk0HntMewJMVZI6RgvN2jT_9Br8MSfZmvUL3sGxBNXaj6QJlYfjzieHoNMLV3Wx3cVsVt9dNtJUvRkz_nOJX8srcA_ACkkvJbjL97_0f2BxcvugI</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Ueno, Midori</creator><creator>Egashira, Ryoko</creator><creator>Hashisako, Mikiko</creator><creator>Fujimoto, Kiminori</creator><creator>Fukuda, Taiki</creator><creator>Hayashida, Yoshiko</creator><creator>Sumikawa, Hiromitsu</creator><creator>Tominaga, Junya</creator><creator>Tanaka, Tomonori</creator><creator>Terasaki, Yasuhiro</creator><creator>Fukuoka, Junya</creator><creator>Nishioka, Yasuhiko</creator><creator>Aoki, Takatoshi</creator><creator>Gabata, Toshifumi</creator><creator>Hatabu, Hiroto</creator><creator>Johkoh, Takeshi</creator><general>Springer Nature Singapore</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TK</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0009-0000-1506-1306</orcidid></search><sort><creationdate>20240901</creationdate><title>Idiopathic dendriform pulmonary ossification as the phenotype of interstitial lung abnormalities: CT–pathologic correlation and prevalence</title><author>Ueno, Midori ; Egashira, Ryoko ; Hashisako, Mikiko ; Fujimoto, Kiminori ; Fukuda, Taiki ; Hayashida, Yoshiko ; Sumikawa, Hiromitsu ; Tominaga, Junya ; Tanaka, Tomonori ; Terasaki, Yasuhiro ; Fukuoka, Junya ; Nishioka, Yasuhiko ; Aoki, Takatoshi ; Gabata, Toshifumi ; Hatabu, Hiroto ; Johkoh, Takeshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c492t-e8431771d26e46d5cf1880e87ee469a1cc04e4e3b4013a03104b0d9298849c2c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abnormalities</topic><topic>Adult</topic><topic>Attenuation</topic><topic>Biopsy</topic><topic>Computed tomography</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Fibrosis</topic><topic>Humans</topic><topic>Imaging</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - pathology</topic><topic>Lung Diseases, Interstitial - diagnostic imaging</topic><topic>Lung Diseases, Interstitial - pathology</topic><topic>Lungs</topic><topic>Male</topic><topic>Malignancy</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastases</topic><topic>Middle Aged</topic><topic>Nuclear Medicine</topic><topic>Original</topic><topic>Original Article</topic><topic>Ossification</topic><topic>Ossification, Heterotopic - diagnostic imaging</topic><topic>Ossification, Heterotopic - pathology</topic><topic>Phenotype</topic><topic>Phenotypes</topic><topic>Prevalence</topic><topic>Radiology</topic><topic>Radiotherapy</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ueno, Midori</creatorcontrib><creatorcontrib>Egashira, Ryoko</creatorcontrib><creatorcontrib>Hashisako, Mikiko</creatorcontrib><creatorcontrib>Fujimoto, Kiminori</creatorcontrib><creatorcontrib>Fukuda, Taiki</creatorcontrib><creatorcontrib>Hayashida, Yoshiko</creatorcontrib><creatorcontrib>Sumikawa, Hiromitsu</creatorcontrib><creatorcontrib>Tominaga, Junya</creatorcontrib><creatorcontrib>Tanaka, Tomonori</creatorcontrib><creatorcontrib>Terasaki, Yasuhiro</creatorcontrib><creatorcontrib>Fukuoka, Junya</creatorcontrib><creatorcontrib>Nishioka, Yasuhiko</creatorcontrib><creatorcontrib>Aoki, Takatoshi</creatorcontrib><creatorcontrib>Gabata, Toshifumi</creatorcontrib><creatorcontrib>Hatabu, Hiroto</creatorcontrib><creatorcontrib>Johkoh, Takeshi</creatorcontrib><collection>Springer Nature OA/Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Japanese journal of radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ueno, Midori</au><au>Egashira, Ryoko</au><au>Hashisako, Mikiko</au><au>Fujimoto, Kiminori</au><au>Fukuda, Taiki</au><au>Hayashida, Yoshiko</au><au>Sumikawa, Hiromitsu</au><au>Tominaga, Junya</au><au>Tanaka, Tomonori</au><au>Terasaki, Yasuhiro</au><au>Fukuoka, Junya</au><au>Nishioka, Yasuhiko</au><au>Aoki, Takatoshi</au><au>Gabata, Toshifumi</au><au>Hatabu, Hiroto</au><au>Johkoh, Takeshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Idiopathic dendriform pulmonary ossification as the phenotype of interstitial lung abnormalities: CT–pathologic correlation and prevalence</atitle><jtitle>Japanese journal of radiology</jtitle><stitle>Jpn J Radiol</stitle><addtitle>Jpn J Radiol</addtitle><date>2024-09-01</date><risdate>2024</risdate><volume>42</volume><issue>9</issue><spage>993</spage><epage>1002</epage><pages>993-1002</pages><issn>1867-1071</issn><issn>1867-108X</issn><eissn>1867-108X</eissn><abstract>Background and purpose
Idiopathic dendriform pulmonary ossification (DPO) is mostly asymptomatic, and detected incidentally in lung CT. There have been no reports on the precise CT–pathologic correlation and the prevalence of idiopathic DPO. This study aimed to clarify the histological background and prevalence of idiopathic DPO.
Materials and methods
Sixteen patients with histologically confirmed idiopathic DPO (12 men and 4 women; mean age, 38.8 years; range 22–56 years) were identified in a nationwide epidemiological survey. Local HRCT findings of pre-biopsy examinations, such as branching, round, linear structures with or without high attenuation were compared side by side with histological findings. The attenuation of branching, round, and linear structures was classified into three-point levels on bone window images (width, 2500 HU; level, 500 HU). Furthermore, we collected continuous pulmonary CT images of 8111 cases for checking up metastasis from extrathoracic malignancy at a single institution, and evaluated the prevalence of interstitial lung abnormalities (ILAs) and DPO.
Results
In all 16 cases, branching (
n
= 15, 93%), round (
n
= 5, 31%), or linear (
n
= 5, 31%) structures were identified, histologically corresponding to dendriform ossification and cicatricial organizing pneumonia (OP)/fibrosis. Histologically, ossification was confirmed in all the 16 patients. However, in two cases, a highly attenuated structure could not be detected on the pre-biopsy CT of the same area. Regarding the prevalence of idiopathic DPO, 283 (3.5%) of 8111 patients had ILAs, of which a total of 26 (0.3% of all cases, 9.2% of ILAs cases) had DPO.
Conclusion
Idiopathic DPO showed linear or branching structures with or without high attenuation on CT, corresponded to ossification, cicatricial OP/fibrosis. DPO was seen in 9.2% of ILAs cases. Idiopathic DPO is one of pathologic phenotypes of ILAs.</abstract><cop>Singapore</cop><pub>Springer Nature Singapore</pub><pmid>38740642</pmid><doi>10.1007/s11604-024-01590-8</doi><tpages>10</tpages><orcidid>https://orcid.org/0009-0000-1506-1306</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Japanese journal of radiology, 2024-09, Vol.42 (9), p.993-1002 |
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| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Abnormalities Adult Attenuation Biopsy Computed tomography Epidemiology Female Fibrosis Humans Imaging Lung - diagnostic imaging Lung - pathology Lung Diseases, Interstitial - diagnostic imaging Lung Diseases, Interstitial - pathology Lungs Male Malignancy Medical imaging Medicine Medicine & Public Health Metastases Middle Aged Nuclear Medicine Original Original Article Ossification Ossification, Heterotopic - diagnostic imaging Ossification, Heterotopic - pathology Phenotype Phenotypes Prevalence Radiology Radiotherapy Tomography, X-Ray Computed - methods Young Adult |
| title | Idiopathic dendriform pulmonary ossification as the phenotype of interstitial lung abnormalities: CT–pathologic correlation and prevalence |
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