The effect of increasing nucleotide-sugar concentrations on the incorporation of sugars into glycoconjugates in rat hepatocytes

Treatment of rat hepatocytes with 0.5 mM concentrations of uridine and cytidine results in increased cellular concentrations of UTP, UDP-sugars and CTP, whereas that of CMP-N-acetylneuraminate remained unchanged [Pels Rijcken, Overdijk, Van den Eijnden and Ferwerda (1993) Biochem. J. 293, 207-213]....

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Veröffentlicht in:	Biochemical journal 1995-02, Vol.305 ( Pt 3) (3), p.865-870
Hauptverfasser:	Pels Rijcken, W R, Overdijk, B, Van den Eijnden, D H, Ferwerda, W
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylglucosamine - metabolism Animals Carbohydrate Metabolism Carbohydrates - pharmacology Cytidine - pharmacology Cytidine Monophosphate N-Acetylneuraminic Acid - metabolism Cytidine Triphosphate - metabolism Fucose - metabolism Glucosamine - metabolism Glycoconjugates - metabolism Hexosamines - metabolism Liver - drug effects Liver - metabolism Male Mannose - metabolism Nucleotides - metabolism Nucleotides - pharmacology Rats Rats, Wistar Tritium Uridine - pharmacology Uridine Diphosphate N-Acetylglucosamine - metabolism Uridine Triphosphate - metabolism
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