Polygonatum sibiricum Polysaccharides Alleviate Depressive-like Symptoms in Chronic Restraint Stress-Induced Mice via Microglial Regulation in Prefrontal Cortex

Microglia respond to stressors by secreting cytokines or growth factors, playing a crucial role in maintaining brain homeostasis. While the antidepressant-like effects of polysaccharides (PSPs) have been observed in mice, their potential effectiveness involving microglial regulation remains unknown....

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Veröffentlicht in:	Polymers 2024-08, Vol.16 (16), p.2358
Hauptverfasser:	Yuan, Zhong-Yu, Zhang, Xuan, Yu, Zong-Zhong, Wang, Xin-Yu, Zeng, Zi-Heng, Wei, Meng-Xuan, Qiu, Meng-Ting, Wang, Jun, Cheng, Jie, Yi, Li-Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antidepressants Atomic properties Atomic structure Brain Brain research Constraints Cytokines Depression, Mental Drug dosages Ethanol Gel chromatography Growth factors Homeostasis Humidity Laboratory animals Medical research Mental depression Mental disorders Metabolism Microscopy Neurophysiology Polysaccharides Spectrum analysis Sucrose Suicides & suicide attempts Water
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