Effect of Mutant and Engineered High-Acetate-Producing Saccharomyces cerevisiae var. boulardii Strains in Dextran Sodium Sulphate-Induced Colitis

Acetate-producing var. strains could exert improved effects on ulcerative colitis, which here, was preclinically evaluated in an acute dextran sodium sulphate induced model of colitis. Nine-week-old female mice were divided into 12 groups, receiving either drinking water or 2.75% dextran sodium sulp...

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Veröffentlicht in:	Nutrients 2024-08, Vol.16 (16), p.2668
Hauptverfasser:	Deleu, Sara, Jacobs, Inge, Vazquez Castellanos, Jorge F, Verstockt, Sare, Trindade de Carvalho, Bruna, Subotić, Ana, Verstockt, Bram, Arnauts, Kaline, Deprez, Lowie, Vissers, Eva, Lenfant, Matthias, Vandermeulen, Greet, De Hertogh, Gert, Verbeke, Kristin, Matteoli, Gianluca, Huys, Geert R B, Thevelein, Johan M, Raes, Jeroen, Vermeire, Séverine
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Animals blood Chemokines Colitis - chemically induced Colitis - therapy Colitis, Ulcerative - chemically induced Colitis, Ulcerative - microbiology Colitis, Ulcerative - therapy Colon - metabolism Colon - microbiology Colon - pathology Cytokines dextran Dextran Sulfate Disease Models, Animal Drinking water Ethics Fatty acids Feces Feces - microbiology Female females Gastrointestinal Microbiome gene expression regulation histology Inflammation Inflammatory bowel disease intestinal microorganisms Metabolism Metabolites Mice Mice, Inbred C57BL mutants Mutation phosphates Probiotics Saccharomyces boulardii Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Sample size sodium sodium sulfate species diversity transcriptomics ulcerative colitis Yeast yeasts
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