The Value of Mandibular Indices on Cone Beam Computed Tomography in Secondary Causes of Low Bone Mass
As implant treatment cases increase, many cases of failure/side effects also occur. Generally, dental clinics determine the density of the jawbone using cone beam CT (CBCT). Considering the known potential role of this tool for bone assessment in primary osteoporosis, this study evaluated patients w...
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creator | Poiană, Ioana Ruxandra Dobre, Ramona Pițuru, Silviu-Mirel Bucur, Alexandru |
description | As implant treatment cases increase, many cases of failure/side effects also occur. Generally, dental clinics determine the density of the jawbone using cone beam CT (CBCT). Considering the known potential role of this tool for bone assessment in primary osteoporosis, this study evaluated patients with secondary endocrine causes of low bone mass.
The study included 83 patients with endocrine causes of osteoporosis who were evaluated by dual-energy X-ray absorptiometry (DXA), trabecular bone score (TBS), and mental foramen (MF) region CBCT. The following CBCT indices were measured: anterior (A)-thickness of inferior mandibular cortex 10 mm anterior from MF; molar (M)-thickness of inferior mandibular cortex 10 mm posterior from MF; posterior (P)-thickness of inferior mandibular cortex 25 mm posterior from MF; symphysis (S)-thickness of inferior mandibular cortex equidistant from the centers of right and left MF.
The highest correlation coefficient in the secondary causes group was between the A index and the lumbar BMD (r = 0.375,
= 0.001) and the P index and the femoral neck BMD (r = 0.38,
= 0.001). Hypercortisolism seems to be the most predictable cause of secondary osteoporosis using the A, M, and P indices. The A, M, and P indices showed predictive values of the bone micro-architecture that was evaluated using TBS score, and were statistically significant. The symphysis index does not significantly predict osteoporosis or impaired bone micro-architecture.
These findings support the potential usefulness of A, M, and P CBCT-derived radiomorphometric mandibular indices in secondary osteoporosis, underlining the well-known effects of these pathologies on bone micro-architecture rather than bone quantity. |
doi_str_mv | 10.3390/jcm13164854 |
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The study included 83 patients with endocrine causes of osteoporosis who were evaluated by dual-energy X-ray absorptiometry (DXA), trabecular bone score (TBS), and mental foramen (MF) region CBCT. The following CBCT indices were measured: anterior (A)-thickness of inferior mandibular cortex 10 mm anterior from MF; molar (M)-thickness of inferior mandibular cortex 10 mm posterior from MF; posterior (P)-thickness of inferior mandibular cortex 25 mm posterior from MF; symphysis (S)-thickness of inferior mandibular cortex equidistant from the centers of right and left MF.
The highest correlation coefficient in the secondary causes group was between the A index and the lumbar BMD (r = 0.375,
= 0.001) and the P index and the femoral neck BMD (r = 0.38,
= 0.001). Hypercortisolism seems to be the most predictable cause of secondary osteoporosis using the A, M, and P indices. The A, M, and P indices showed predictive values of the bone micro-architecture that was evaluated using TBS score, and were statistically significant. The symphysis index does not significantly predict osteoporosis or impaired bone micro-architecture.
These findings support the potential usefulness of A, M, and P CBCT-derived radiomorphometric mandibular indices in secondary osteoporosis, underlining the well-known effects of these pathologies on bone micro-architecture rather than bone quantity.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm13164854</identifier><identifier>PMID: 39200996</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Bone density ; CT imaging ; Dental implants ; Diagnosis ; Endocrinology ; Fractures ; Hyperthyroidism ; Mandible ; Medical diagnosis ; Medical examination ; Methods ; Osteoporosis ; Tomography</subject><ispartof>Journal of clinical medicine, 2024-08, Vol.13 (16), p.4854</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2024 by the authors. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11355527/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11355527/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39200996$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Poiană, Ioana Ruxandra</creatorcontrib><creatorcontrib>Dobre, Ramona</creatorcontrib><creatorcontrib>Pițuru, Silviu-Mirel</creatorcontrib><creatorcontrib>Bucur, Alexandru</creatorcontrib><title>The Value of Mandibular Indices on Cone Beam Computed Tomography in Secondary Causes of Low Bone Mass</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>As implant treatment cases increase, many cases of failure/side effects also occur. Generally, dental clinics determine the density of the jawbone using cone beam CT (CBCT). Considering the known potential role of this tool for bone assessment in primary osteoporosis, this study evaluated patients with secondary endocrine causes of low bone mass.
The study included 83 patients with endocrine causes of osteoporosis who were evaluated by dual-energy X-ray absorptiometry (DXA), trabecular bone score (TBS), and mental foramen (MF) region CBCT. The following CBCT indices were measured: anterior (A)-thickness of inferior mandibular cortex 10 mm anterior from MF; molar (M)-thickness of inferior mandibular cortex 10 mm posterior from MF; posterior (P)-thickness of inferior mandibular cortex 25 mm posterior from MF; symphysis (S)-thickness of inferior mandibular cortex equidistant from the centers of right and left MF.
The highest correlation coefficient in the secondary causes group was between the A index and the lumbar BMD (r = 0.375,
= 0.001) and the P index and the femoral neck BMD (r = 0.38,
= 0.001). Hypercortisolism seems to be the most predictable cause of secondary osteoporosis using the A, M, and P indices. The A, M, and P indices showed predictive values of the bone micro-architecture that was evaluated using TBS score, and were statistically significant. The symphysis index does not significantly predict osteoporosis or impaired bone micro-architecture.
These findings support the potential usefulness of A, M, and P CBCT-derived radiomorphometric mandibular indices in secondary osteoporosis, underlining the well-known effects of these pathologies on bone micro-architecture rather than bone quantity.</description><subject>Bone density</subject><subject>CT imaging</subject><subject>Dental implants</subject><subject>Diagnosis</subject><subject>Endocrinology</subject><subject>Fractures</subject><subject>Hyperthyroidism</subject><subject>Mandible</subject><subject>Medical diagnosis</subject><subject>Medical examination</subject><subject>Methods</subject><subject>Osteoporosis</subject><subject>Tomography</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptUU1vGyEURFWqJkpz6r1C6qUXp7DAAqcqsZoPyVEPdXJFb5e3NtYuuIs3Vf59sJq2SRU4MOLNzGMehHzg7FQIy75s2oELXkuj5BtyVDGtZ0wYcfAMH5KTnDesLGNkxfU7cihsxZi19RHB5RrpHfQT0tTRG4g-NFMPI70uqMVMU6TzFJGeIwwFDdtph54u05BWI2zXDzRE-gPbFD2MD3QOU96LOrpIv-j5XngDOb8nbzvoM548ncfk9uLbcn41W3y_vJ6fLWYrUdndDKWva2m7RjTcSs68glYo1SnTSAWmJALf1SANqwywxpQa6AYAvEDGWS2OydffvtupGdC3GHcj9G47hqG8ziUI7mUlhrVbpXvHefFSlS4On58cxvRzwrxzQ8gt9j1ETFN2ooyNSyG1KtRP_1E3aRpjybdnaau05tU_1gp6dCF2qTRu96buzDDDLeNWFNbpK6yyPQ6hDBe7UO5fCD4-T_o34p-fFY9QPKNK</recordid><startdate>20240816</startdate><enddate>20240816</enddate><creator>Poiană, Ioana Ruxandra</creator><creator>Dobre, Ramona</creator><creator>Pițuru, Silviu-Mirel</creator><creator>Bucur, Alexandru</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240816</creationdate><title>The Value of Mandibular Indices on Cone Beam Computed Tomography in Secondary Causes of Low Bone Mass</title><author>Poiană, Ioana Ruxandra ; Dobre, Ramona ; Pițuru, Silviu-Mirel ; Bucur, Alexandru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g329t-e4d6649fb3b19410d5ac355f58b45a8207adf6a48028a0b8355a7baaad3e01063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Bone density</topic><topic>CT imaging</topic><topic>Dental implants</topic><topic>Diagnosis</topic><topic>Endocrinology</topic><topic>Fractures</topic><topic>Hyperthyroidism</topic><topic>Mandible</topic><topic>Medical diagnosis</topic><topic>Medical examination</topic><topic>Methods</topic><topic>Osteoporosis</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Poiană, Ioana Ruxandra</creatorcontrib><creatorcontrib>Dobre, Ramona</creatorcontrib><creatorcontrib>Pițuru, Silviu-Mirel</creatorcontrib><creatorcontrib>Bucur, Alexandru</creatorcontrib><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Poiană, Ioana Ruxandra</au><au>Dobre, Ramona</au><au>Pițuru, Silviu-Mirel</au><au>Bucur, Alexandru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Value of Mandibular Indices on Cone Beam Computed Tomography in Secondary Causes of Low Bone Mass</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2024-08-16</date><risdate>2024</risdate><volume>13</volume><issue>16</issue><spage>4854</spage><pages>4854-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>As implant treatment cases increase, many cases of failure/side effects also occur. Generally, dental clinics determine the density of the jawbone using cone beam CT (CBCT). Considering the known potential role of this tool for bone assessment in primary osteoporosis, this study evaluated patients with secondary endocrine causes of low bone mass.
The study included 83 patients with endocrine causes of osteoporosis who were evaluated by dual-energy X-ray absorptiometry (DXA), trabecular bone score (TBS), and mental foramen (MF) region CBCT. The following CBCT indices were measured: anterior (A)-thickness of inferior mandibular cortex 10 mm anterior from MF; molar (M)-thickness of inferior mandibular cortex 10 mm posterior from MF; posterior (P)-thickness of inferior mandibular cortex 25 mm posterior from MF; symphysis (S)-thickness of inferior mandibular cortex equidistant from the centers of right and left MF.
The highest correlation coefficient in the secondary causes group was between the A index and the lumbar BMD (r = 0.375,
= 0.001) and the P index and the femoral neck BMD (r = 0.38,
= 0.001). Hypercortisolism seems to be the most predictable cause of secondary osteoporosis using the A, M, and P indices. The A, M, and P indices showed predictive values of the bone micro-architecture that was evaluated using TBS score, and were statistically significant. The symphysis index does not significantly predict osteoporosis or impaired bone micro-architecture.
These findings support the potential usefulness of A, M, and P CBCT-derived radiomorphometric mandibular indices in secondary osteoporosis, underlining the well-known effects of these pathologies on bone micro-architecture rather than bone quantity.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>39200996</pmid><doi>10.3390/jcm13164854</doi><oa>free_for_read</oa></addata></record> |
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source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
subjects | Bone density CT imaging Dental implants Diagnosis Endocrinology Fractures Hyperthyroidism Mandible Medical diagnosis Medical examination Methods Osteoporosis Tomography |
title | The Value of Mandibular Indices on Cone Beam Computed Tomography in Secondary Causes of Low Bone Mass |
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