Cellular and Molecular Genetic Mechanisms of Lung Fibrosis Development and the Role of Vitamin D: A Review

Idiopathic pulmonary fibrosis remains a relevant problem of the healthcare system with an unfavorable prognosis for patients due to progressive fibrous remodeling of the pulmonary parenchyma. Starting with the damage of the epithelial lining of alveoli, pulmonary fibrosis is implemented through a ca...

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Veröffentlicht in:	International journal of molecular sciences 2024-08, Vol.25 (16), p.8946
Hauptverfasser:	Enzel, Darya, Kriventsov, Maxim, Sataieva, Tatiana, Malygina, Veronika
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DNA methylation Endothelium Epigenetics Fibroblasts Growth factors Humans Idiopathic Pulmonary Fibrosis - genetics Idiopathic Pulmonary Fibrosis - metabolism Idiopathic Pulmonary Fibrosis - pathology Ligands Lungs Medical prognosis MicroRNAs Pathogenesis Pulmonary fibrosis Pulmonary Fibrosis - genetics Pulmonary Fibrosis - metabolism Pulmonary Fibrosis - pathology Quality of life Review Signal Transduction Smoking Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism Vitamin D Vitamin D - metabolism Vitamin D - pharmacology
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