A novel site contributing to growth-arrest-specific gene 6 binding to its receptors as revealed by a human monoclonal antibody

Gas6 (growth-arrest-specific gene 6) is a vitamin K-dependent protein known to activate the Axl family of receptor tyrosine kinases. It is an important regulator of thrombosis and many other biological functions. The C-terminus of Gas6 binds to receptors and consists of two laminin-like globular dom...

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Veröffentlicht in:	Biochemical journal 2005-05, Vol.387 (Pt 3), p.727-735
Hauptverfasser:	Fisher, Paul W, Brigham-Burke, Michael, Wu, Sheng-Jiun, Luo, Jinquan, Carton, Jill, Staquet, Kim, Gao, Wei, Jackson, Sheila, Bethea, Deidra, Chen, Cailin, Hu, Bing, Giles-Komar, Jill, Yang, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibodies, Monoclonal - chemistry Binding Sites Calcium - chemistry Epitope Mapping Humans Intercellular Signaling Peptides and Proteins - chemistry Kinetics Molecular Sequence Data Protein Binding Protein Structure, Tertiary
Online-Zugang:	Volltext
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