Molecular relapse after first-line intensive therapy in patients with CBF or NPM1-mutated acute myeloid leukemia – a FILO study

Patients with Core-Binding Factor (CBF) and NPM1 -mutated acute myeloid leukemia (AML) can be monitored by quantitative PCR after having achieved first complete remission (CR) to detect morphologic relapse and drive preemptive therapy. How to best manage these patients is unknown. We retrospectively...

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Veröffentlicht in:Leukemia 2024-09, Vol.38 (9), p.1949-1957
Hauptverfasser: Orvain, Corentin, Bertoli, Sarah, Peterlin, Pierre, Desbrosses, Yohann, Dumas, Pierre-Yves, Iat, Alexandre, Hospital, Marie-Anne, Carre, Martin, Tavernier, Emmanuelle, Riou, Jérémie, Bouvier, Anne, Bidet, Audrey, Tondeur, Sylvie, Renosi, Florian, Mozziconacci, Marie-Joelle, Flandrin-Gresta, Pascale, Dadone-Montaudié, Bérengère, Delabesse, Eric, Pigneux, Arnaud, Hunault-Berger, Mathilde, Recher, Christian
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Sprache:eng
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