Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10

Abstract The simian virus 40 (SV40) replisome only encodes for its helicase; large T-antigen (L-Tag), while relying on the host for the remaining proteins, making it an intriguing model system. Despite being one of the earliest reconstituted eukaryotic systems, the interactions coordinating its acti...

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Veröffentlicht in:	Nucleic acids research 2024-08, Vol.52 (15), p.8880-8896
Hauptverfasser:	Ouyang, Yujing, Al-Amodi, Amani, Tehseen, Muhammad, Alhudhali, Lubna, Shirbini, Afnan, Takahashi, Masateru, Raducanu, Vlad-Stefan, Yi, Gang, Danazumi, Ammar Usman, De Biasio, Alfredo, Hamdan, Samir M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Polyomavirus Transforming - genetics Antigens, Polyomavirus Transforming - metabolism DNA Helicases - genetics DNA Helicases - metabolism DNA Polymerase III - genetics DNA Polymerase III - metabolism DNA Replication DNA, Single-Stranded - metabolism DNA, Viral - genetics DNA, Viral - metabolism DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism DNA-Directed DNA Polymerase Genome Integrity, Repair and Humans Minichromosome Maintenance Proteins - genetics Minichromosome Maintenance Proteins - metabolism Multienzyme Complexes Replication Protein A - metabolism Simian virus 40 - genetics Simian virus 40 - metabolism Single Molecule Imaging Virus Replication
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