A cryptic matrix targeting signal of the yeast ADP/ATP carrier normally inserted by the TIM22 complex is recognized by the TIM23 machinery

The yeast ADP/ATP carrier (AAC) is a mitochondrial protein that is targeted to the inner membrane via the TIM10 and TIM22 translocase complexes. AAC is devoid of a typical mitochondrial targeting signal and its targeting and insertion are thought to be guided by internal amino acid sequences. Here w...

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Veröffentlicht in:Biochemical journal 2005-01, Vol.385 (Pt 1), p.173-180
Hauptverfasser: Vergnolle, Maïlys A S, Sawney, Helen, Junne, Tina, Dolfini, Luisita, Tokatlidis, Kostas
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Sprache:eng
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