Stabilin-2 mediated apoptotic cell phagocytosis induces interleukin-10 expression by p38 and Pbx1 signaling

Apoptotic cell death occurs under normal physiological conditions, such as development, tissue remodeling, and inflammation. Appropriate removal of apoptotic cells by phagocytes and the secretion of anti-inflammatory cytokines such as IL-10 are important mechanisms for maintaining tissue homeostasis...

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Veröffentlicht in:	Cell biochemistry and biophysics 2024-06, Vol.82 (2), p.919-925
Hauptverfasser:	Jo, Han-Seul, Kim, Ha-Jeong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Apoptosis Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Biotechnology Cell Adhesion Molecules - metabolism Cell Adhesion Molecules, Neuronal - genetics Cell Adhesion Molecules, Neuronal - metabolism Cell Biology Cell death Cells Cytokines Cytoskeleton Epidermal growth factor Epithelial cells Epithelium Flow cytometry Gene regulation Homeostasis Humans Inflammation Interleukin 10 Interleukin-10 - metabolism Kinases Life Sciences Macrophages Medical research Mice Original Paper p38 Mitogen-Activated Protein Kinases - metabolism Phagocytes Phagocytosis Pharmacology/Toxicology Phosphatidylserine Proteins Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Receptors Recognition Signal Transduction Transcription Factors - genetics Transcription Factors - metabolism
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