Effect of 25-hydroxycholesterol and bile acids on the regulation of cholesterol metabolism in Hep G2 cells

The effect of 25-hydroxycholesterol (25-OH-cholesterol) and chenodeoxycholic (CDC) acid on apoprotein secretion, low-density lipoprotein receptor activity, and [3H]triacylglycerol secretion in Hep G2 cells was studied. Both 25-OH-cholesterol and CDC acid increased the secretion of apolipoprotein (ap...

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Veröffentlicht in:	Biochemical journal 1989-11, Vol.264 (1), p.241-247
Hauptverfasser:	Carlson, T L, Kottke, B A
Format:	Artikel
Sprache:	eng
Schlagworte:	25-hydroxycholesterol Apolipoprotein A-I Apolipoproteins A - metabolism Apolipoproteins E - genetics Apolipoproteins E - metabolism bile Chenodeoxycholic Acid - pharmacology Cholesterol - metabolism Humans Hydroxycholesterols - pharmacology In Vitro Techniques Lipoproteins, LDL - metabolism Liver - metabolism Lovastatin - pharmacology Receptors, LDL - metabolism RNA, Messenger - metabolism Triglycerides - metabolism Tumor Cells, Cultured
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