The prevalence of myocardial infarction in the elderly: A systematic review and meta-analysis
Myocardial Infarction (MI) refers to the destruction and death of cells in the myocardium of the heart. Its prevalence increases with age due to changes in the cardiovascular system. The aim of the present study was to combine, summarize, standardize, resolve inconsistencies in the results of studie...
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| Veröffentlicht in: | ARYA atherosclerosis 2024-03, Vol.20 (2), p.61-73 |
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| creator | Rajati, Fatemeh Rajati, Mojgan Chegeni, Maryam Kazeminia, Mohsen |
| description | Myocardial Infarction (MI) refers to the destruction and death of cells in the myocardium of the heart. Its prevalence increases with age due to changes in the cardiovascular system. The aim of the present study was to combine, summarize, standardize, resolve inconsistencies in the results of studies, and investigate the impact of potential factors on the prevalence rate of MI in the elderly through a systematic review and meta-analysis.
This systematic review and meta-analysis was conducted from 1987 to March 2022. All relevant published studies were searched in PubMed, Embase, Scopus, Web of Science (WoS) databases, and Google Scholar search engine using related MeSH/Emtree and Free Text words. The heterogeneity among studies was quantified using the I
index.
In the initial search, 35453 studies were identified. After eliminating irrelevant studies, finally, 29 articles with a sample size of 3279136 subjects were included in the meta-analysis. After combining the results of the studies included in the meta-analysis, the total prevalence of MI in the elderly was estimated to be 17.6% (95% CI: 12.8 - 23.7%), 16.1% (95% CI: 11.0 - 22.8%) in males, and 12.5% (95% CI: 9.2 - 16.8%) in females. The prevalence of MI increased with the year of publication and the mean age of the elderly (P < 0.001).
The results showed that due to the high prevalence of myocardial infarction (MI) in the elderly, it should be addressed within healthcare systems and policy makers should pay more attention to prevention of MI. However, considering the inclusion of heterogeneous studies, the pooled estimation should be interpreted with caution. |
| doi_str_mv | 10.48305/arya.2024.42327.2930 |
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This systematic review and meta-analysis was conducted from 1987 to March 2022. All relevant published studies were searched in PubMed, Embase, Scopus, Web of Science (WoS) databases, and Google Scholar search engine using related MeSH/Emtree and Free Text words. The heterogeneity among studies was quantified using the I
index.
In the initial search, 35453 studies were identified. After eliminating irrelevant studies, finally, 29 articles with a sample size of 3279136 subjects were included in the meta-analysis. After combining the results of the studies included in the meta-analysis, the total prevalence of MI in the elderly was estimated to be 17.6% (95% CI: 12.8 - 23.7%), 16.1% (95% CI: 11.0 - 22.8%) in males, and 12.5% (95% CI: 9.2 - 16.8%) in females. The prevalence of MI increased with the year of publication and the mean age of the elderly (P < 0.001).
The results showed that due to the high prevalence of myocardial infarction (MI) in the elderly, it should be addressed within healthcare systems and policy makers should pay more attention to prevention of MI. However, considering the inclusion of heterogeneous studies, the pooled estimation should be interpreted with caution.</description><identifier>ISSN: 1735-3955</identifier><identifier>EISSN: 2251-6638</identifier><identifier>DOI: 10.48305/arya.2024.42327.2930</identifier><identifier>PMID: 39170816</identifier><language>eng</language><publisher>Iran: Isfahan Cardiovascular Research Center</publisher><subject>Age ; Atherosclerosis ; Cardiovascular system ; Chronic illnesses ; Chronic obstructive pulmonary disease ; Heart attacks ; Medical Subject Headings-MeSH ; Meta-analysis ; Older people ; Original ; Search strategies ; Statistical analysis ; Systematic review</subject><ispartof>ARYA atherosclerosis, 2024-03, Vol.20 (2), p.61-73</ispartof><rights>2024. This work is published under https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335027/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335027/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39170816$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rajati, Fatemeh</creatorcontrib><creatorcontrib>Rajati, Mojgan</creatorcontrib><creatorcontrib>Chegeni, Maryam</creatorcontrib><creatorcontrib>Kazeminia, Mohsen</creatorcontrib><title>The prevalence of myocardial infarction in the elderly: A systematic review and meta-analysis</title><title>ARYA atherosclerosis</title><addtitle>ARYA Atheroscler</addtitle><description>Myocardial Infarction (MI) refers to the destruction and death of cells in the myocardium of the heart. Its prevalence increases with age due to changes in the cardiovascular system. The aim of the present study was to combine, summarize, standardize, resolve inconsistencies in the results of studies, and investigate the impact of potential factors on the prevalence rate of MI in the elderly through a systematic review and meta-analysis.
This systematic review and meta-analysis was conducted from 1987 to March 2022. All relevant published studies were searched in PubMed, Embase, Scopus, Web of Science (WoS) databases, and Google Scholar search engine using related MeSH/Emtree and Free Text words. The heterogeneity among studies was quantified using the I
index.
In the initial search, 35453 studies were identified. After eliminating irrelevant studies, finally, 29 articles with a sample size of 3279136 subjects were included in the meta-analysis. After combining the results of the studies included in the meta-analysis, the total prevalence of MI in the elderly was estimated to be 17.6% (95% CI: 12.8 - 23.7%), 16.1% (95% CI: 11.0 - 22.8%) in males, and 12.5% (95% CI: 9.2 - 16.8%) in females. The prevalence of MI increased with the year of publication and the mean age of the elderly (P < 0.001).
The results showed that due to the high prevalence of myocardial infarction (MI) in the elderly, it should be addressed within healthcare systems and policy makers should pay more attention to prevention of MI. However, considering the inclusion of heterogeneous studies, the pooled estimation should be interpreted with caution.</description><subject>Age</subject><subject>Atherosclerosis</subject><subject>Cardiovascular system</subject><subject>Chronic illnesses</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Heart attacks</subject><subject>Medical Subject Headings-MeSH</subject><subject>Meta-analysis</subject><subject>Older people</subject><subject>Original</subject><subject>Search strategies</subject><subject>Statistical analysis</subject><subject>Systematic review</subject><issn>1735-3955</issn><issn>2251-6638</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkF9LHTEQxUOp1Iv6ESqBvvRlr0lmk018KSL1Dwh90UdZ5m5mNZLdvU32KvvtG6qVtvMyA_Obw5nD2Gcp1rUFoU8wLbhWQtXrWoFq1sqB-MBWSmlZGQP2I1vJBnQFTut9dpTzkygFyppafWL74GQjrDQrdn_7SHyb6BkjjR3xqefDMnWYfMDIw9hj6uYwjWXkc0EpekpxOeVnPC95pgHn0PFyH-iF4-j5QDNWOGJccsiHbK_HmOnorR-wu4vvt-dX1c2Py-vzs5tqWxzPVfmocxKMl7031Es0UsDGkkELXvjGG_SoN86QI6kNKN844YXaKG21AAEH7Nur7na3Gch3NM4JY7tNYShJtROG9t_NGB7bh-m5lRJAC9UUha9vCmn6uaM8t0PIHcWII0273IJw2tgSry3ol__Qp2mXyse_KeEao2pdqOO_Lb17-RM9_AJfXIig</recordid><startdate>20240301</startdate><enddate>20240301</enddate><creator>Rajati, Fatemeh</creator><creator>Rajati, Mojgan</creator><creator>Chegeni, Maryam</creator><creator>Kazeminia, Mohsen</creator><general>Isfahan Cardiovascular Research Center</general><general>Cardiovascular research institute, Isfahan University of Medical Sciences</general><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20240301</creationdate><title>The prevalence of myocardial infarction in the elderly: A systematic review and meta-analysis</title><author>Rajati, Fatemeh ; 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Its prevalence increases with age due to changes in the cardiovascular system. The aim of the present study was to combine, summarize, standardize, resolve inconsistencies in the results of studies, and investigate the impact of potential factors on the prevalence rate of MI in the elderly through a systematic review and meta-analysis.
This systematic review and meta-analysis was conducted from 1987 to March 2022. All relevant published studies were searched in PubMed, Embase, Scopus, Web of Science (WoS) databases, and Google Scholar search engine using related MeSH/Emtree and Free Text words. The heterogeneity among studies was quantified using the I
index.
In the initial search, 35453 studies were identified. After eliminating irrelevant studies, finally, 29 articles with a sample size of 3279136 subjects were included in the meta-analysis. After combining the results of the studies included in the meta-analysis, the total prevalence of MI in the elderly was estimated to be 17.6% (95% CI: 12.8 - 23.7%), 16.1% (95% CI: 11.0 - 22.8%) in males, and 12.5% (95% CI: 9.2 - 16.8%) in females. The prevalence of MI increased with the year of publication and the mean age of the elderly (P < 0.001).
The results showed that due to the high prevalence of myocardial infarction (MI) in the elderly, it should be addressed within healthcare systems and policy makers should pay more attention to prevention of MI. However, considering the inclusion of heterogeneous studies, the pooled estimation should be interpreted with caution.</abstract><cop>Iran</cop><pub>Isfahan Cardiovascular Research Center</pub><pmid>39170816</pmid><doi>10.48305/arya.2024.42327.2930</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Age Atherosclerosis Cardiovascular system Chronic illnesses Chronic obstructive pulmonary disease Heart attacks Medical Subject Headings-MeSH Meta-analysis Older people Original Search strategies Statistical analysis Systematic review |
| title | The prevalence of myocardial infarction in the elderly: A systematic review and meta-analysis |
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