Metal π-Lewis base activation in palladium(0)-catalyzed trans -alkylative cyclization of alkynals

The Pd(0)-mediated umpolung reaction of an alkyne to achieve -difunctionalization is a potential synthetic methodology, but its insightful activation mechanism of Pd(0)-alkyne interaction has yet to be established. Here, a Pd(0)-π-Lewis base activation mode is proposed and investigated by combining...

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Veröffentlicht in:	Chemical science (Cambridge) 2024-08, Vol.15 (32), p.13032-13040
Hauptverfasser:	Zhu, Lei, Zhao, Bo, Xie, Ke, Gui, Wu-Tao, Niu, Sheng-Li, Zheng, Peng-Fei, Chen, Ying-Chun, Qi, Xiao-Wei, Ouyang, Qin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Alkylation Alkynes Chemistry Lewis base Palladium Substrates
Online-Zugang:	Volltext
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