Vagus nerve stimulation alleviates cardiac dysfunction and inflammatory markers during heart failure in rats

Vagus nerve stimulation (VNS) is under clinical investigation as a therapy for heart failure with reduced ejection fraction (HFrEF). This study aimed to investigate its therapeutic effects on three main components of heart failure: cardiac function, cardiac remodeling and central neuroinflammation u...

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Veröffentlicht in:	Autonomic neuroscience 2024-06, Vol.253, p.103162-103162, Article 103162
Hauptverfasser:	Owens, Misty M., Dalal, Suman, Radovic, Aleksandra, Fernandes, Luciano, Syed, Hassan, Herndon, Mary-Katherine, Cooper, Coty, Singh, Krishna, Beaumont, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiac hypertrophy Disease Models, Animal Heart failure Heart Failure - physiopathology Heart Failure - therapy Inflammation - physiopathology Inflammation - therapy Male Neuroinflammation Neuroinflammatory Diseases - physiopathology Neuroinflammatory Diseases - therapy Pressure overload Rat Rats Rats, Sprague-Dawley Stroke Volume - physiology Vagus nerve stimulation Vagus Nerve Stimulation - methods Ventricular Remodeling - physiology
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