Liver inositol, 1,4,5-trisphosphate-binding sites are the Ca2(+)-mobilizing receptors

Ins(1,4,5)P3 is the intracellular messenger that in many cells mediates the effects of Ca2(+)-mobilizing receptors on intracellular Ca2+ stores. An Ins(1,4,5)P3 receptor from cerebellum has been purified and functionally reconstituted, but the relationship between this protein and the high-affinity...

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Veröffentlicht in:	Biochemical journal 1990-08, Vol.270 (1), p.227-232
Hauptverfasser:	Nunn, D L, Taylor, C W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - pharmacology Animals Binding Sites Calcium - metabolism Cerebellum - metabolism In Vitro Techniques Inositol 1,4,5-Trisphosphate - metabolism Inositol Phosphates - metabolism Kinetics Ligands Liver - metabolism Molecular Weight Rats Receptors, Cell Surface - metabolism Signal Transduction
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