Long-term treatment of isolated rat soleus muscle with phorbol ester leads to loss of contraction-induced glucose transport

Muscle contraction involves mobilization of intracellular Ca2+ and is associated with several metabolic adjustments, including increased glucose transport. In the present study isolated rat soleus muscles were exposed to 12-O-tetradecanoylphorbol 13-acetate, and responses to both insulin and contrac...

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Veröffentlicht in:Biochemical journal 1990-05, Vol.267 (3), p.659-663
Hauptverfasser: Cleland, P J, Abel, K C, Rattigan, S, Clark, M G
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Sprache:eng
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