Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report

Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report

Neuroleptic malignant syndrome (NMS) is a rare but fatal condition, with a high mortality rate. NMS is characterized by altered mental status, fever, myoclonus, autonomic dysfunctions, and elevated creatinine phosphokinase. The clinical manifestations may be confused with alcohol-related symptoms, t...

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Veröffentlicht in:Daehan oe'sang haghoeji 2023-09, Vol.36 (3), p.249-252
Hauptverfasser: Yu, Byungchul, Lee, Ji Yeon, Kim, Yong Beom, Park, Hee Yeon, Jung, Junsu, Jo, Youn Yi
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Case Report
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container_end_page 252
container_issue 3
container_start_page 249
container_title Daehan oe'sang haghoeji
container_volume 36
creator Yu, Byungchul
Lee, Ji Yeon
Kim, Yong Beom
Park, Hee Yeon
Jung, Junsu
Jo, Youn Yi
description Neuroleptic malignant syndrome (NMS) is a rare but fatal condition, with a high mortality rate. NMS is characterized by altered mental status, fever, myoclonus, autonomic dysfunctions, and elevated creatinine phosphokinase. The clinical manifestations may be confused with alcohol-related symptoms, trauma, sepsis, postoperative agitation, or malignant hyperthermia. A 69-year-old male patient with alcohol withdrawal was admitted to the operating theatre to rule out septic shock due to mesenteric injury after multiple trauma. He was suspected NMS with abrupt increase body temperature to 41.7°C after haloperidol administration. Active cooling and rapid fluid infusion was done during anesthesia. Delayed diagnosis and treatment of NMS lead to catastrophic result. Therefore, if the patient's past medical history is unknown or clinical symptoms develop that are suggestive of NMS, early treatment must be considered.
doi_str_mv 10.20408/jti.2022.0048
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subjects Case Report
title Management of a trauma patient with alcohol withdrawal who developed neuroleptic malignant syndrome in Korea: a case report
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