Impact of Physical Exercise on Levodopa Therapy Across Parkinson’s Disease Stages

Background: Levodopa is the gold standard of treatment in Parkinson’s disease (PD). Its clinical effect changes as the disease progresses. Wearing off is a frequent first manifestation of motor fluctuations. Some patients with advanced PD report faster wearing off after physical exercise. Objective:...

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Veröffentlicht in:	Journal of Parkinson's disease 2024-01, Vol.14 (5), p.1039-1049
Hauptverfasser:	Figura, Monika, Mrozowicz, Agnieszka, Milanowski, Łukasz, Szlufik, Stanisław, Raćkowska, Emilia, Lypkan, Hanna, Friedman, Andrzej, Koziorowski, Dariusz, Giebułtowicz, Joanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antiparkinson Agents - administration & dosage Antiparkinson Agents - blood Antiparkinson Agents - pharmacokinetics Benserazide - administration & dosage Benserazide - pharmacology Disease Progression Drug Combinations Exercise Exercise - physiology Female Humans Levodopa Levodopa - administration & dosage Levodopa - pharmacokinetics Liquid chromatography Male Mass spectroscopy Middle Aged Movement disorders Neurodegenerative diseases Parkinson Disease - blood Parkinson Disease - drug therapy Parkinson Disease - therapy Parkinson's disease Patients Pharmacokinetics Research Report Severity of Illness Index
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